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Table 3 Concordance index (C-index) and Akaike Information Criterion (AIC) as measures of model fit for CKD progression and accelerated eGFR decline in patients with type 2 diabetes

From: Addition of nonalbumin proteinuria to albuminuria improves prediction of type 2 diabetic nephropathy progression

  Univariate analysis Multivariate analysisa
C-index AIC C-index AIC
CKD progression
 Model 1 0.650 235.363 0.721 243.728
 Model 2 0.708 227.673 0.772 235.669
 Model 3 0.745 225.506 0.801 234.306
Accelerated eGFR decline
 Model 1 0.552 715.307 0.625 710.887
 Model 2 0.585 712.069 0.648 707.140
 Model 3 0.592 714.638 0.648 710.365
  1. Model 1, vs. normoalbuminuria; model 2, vs. NAPCR levels below 120 mg/g; model 3, vs. normoalbuminuria and NAPCR levels below 120 mg/g
  2. aAdjusted for age, sex, duration of diabetes, SBP, LDL, HbA1c, baseline eGFR, RAS inhibitor use and lipid-lowering agent use