Table 3 Clinical profiles of groups according to histological classification of NAFLD by Mateonni

n

17

38

22

54

Age

39.4 ± 3.1

41.3 ± 2.8

51.9 ± 3.6

50.0 ± 2.1

Sex (M/F)

12/5

22/16

12/10

27/27

BMI (kg/m²)

28.5 ± 1.5

29.8 ± 0.8

26.8 ± 0.9

29.4 ± 0.7

HbA1c (%)

4.99 ± 0.10

5.39 ± 0.13

5.99 ± 0.30*

5.55 ± 0.11

G₀ (mmol/L)

5.16 ± 0.11

5.69 ± 0.15

6.12 ± 0.36

5.87 ± 0.20

G₁₂₀ (mmol/L)

8.01 ± 0.53

9.35 ± 0.59

10.80 ± 1.10

10.17 ± 0.51

G_m (mmol/L)

8.88 ± 0.30

9.58 ± 0.38

10.68 ± 0.75

10.27 ± 0.40

I₀ (pmol/L)

48.7 ± 9.4

81.3 ± 8.5

74.4 ± 10.4

88.3 ± 8.6

I₁₂₀ (pmol/L)

568.0 ± 134.9

638.9 ± 77.9

536.4 ± 72.7

704.4 ± 65.6

I_m (pmol/L)

516.3 ± 84.5

493.9 ± 55.6

395.6 ± 49.5

561.6 ± 48.0

IGI (pmol/mmol)

87.6 (32.9, 170.2)

67.9 (39.0, 126.3)

48.7 (35.8, 76.4)

89.4 (43.0, 130.4)

HOMA-β

70 (51, 104)

125 (62, 169)

82 (54, 153)

109 (76, 189)

HOMA-R

1.58 (1.10, 1.85)

3.41 (1.53, 4.11)

2.43 (1.31, 5.39)

3.045 (1.87, 5.16)

QUICKI

0.363 ± 0.010

0.330 ± 0.005

0.333 ± 0.008

0.326 ± 0.004*

Matsuda index

3.20 (2.69, 6.26)

2.88 (1.87, 4.97)

2.79 (1.65, 5.65)

2.65 (1.38, 3.44)

DI_O (mmol/L⁻¹)

2.42 (1.14, 3.81)

1.10* (0.70, 1.59)

1.03* (0.39, 1.45)

1.22* (0.56, 2.08)

OGTT

 NGT n(%)

9 (52.9)

19 (50.0)

6 (27.2)

13 (24.1)

 IGM n(%)

7 (41.2)

9 (23.7)

10 (45.5)

25 (46.3)

 DM n(%)

1 (5.9)

10 (26.3)

6 (27.2)

16 (29.6)