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Table 1 Potential biomarkers of diabetic cardiomyopathy in rats

From: Changes of myocardial lipidomics profiling in a rat model of diabetic cardiomyopathy using UPLC/Q-TOF/MS analysis

No. tR (min) Mass-to-charge (m/z) ratios VIP values P value DCM model versus control Chemical names Structure Fold values
Positive mode
 1 5.7270 830.5688 4.75926 0.000298 PC (22:6/18:2) C48H80NO8P 2.3550
 2 6.2368 832.5842 1.82151 0.000235 PC (22:6/18:1) C48H82NO8P 2.0013
 3 6.6324 764.5216 1.83260 8.78E−05 PE (20:4/18:2) C43H74NO8P 2.1611
 4 8.2759 810.5986 1.21197 0.041959 PC (20:2/18:2) C46H84NO8P 2.3574
 5 8.3776 784.5834 2.92017 0.000513 PC (18:0/16:0) C42H84NO8P 4.3254
 6 8.6115 810.5998 1.89759 1.46E−05 PC (20:4/18:0) or PC (20:3/18:1) C46H84NO8P 6.7733
 7 5.8249 780.5525 1.86694 0.001519 PC (20:4/16:1) C44H78NO8P 3.3939
 8 5.6524 754.5370 1.27221 0.000592 PC (16:1/18:3) C42H76NO8P 4.4684
 9 9.2400 780.5890 1.23109 0.001364 PE (20:4/16:0) C41H74NO8P 3.3926
  1. PC, phosphatidylcholine; PE, phosphatidylethanolamine; tR, retention time; VIP, variable importance in projection; DCM, diabetic cardiomyopathy