Fig. 1

OPLS-DA score plot and loading plot. Scatter plots of diabetic cardiomyopathy (DCM) model and control rats (n = 5 per group) were acquired by ultra-high-performance liquid chromatography coupled with quadruple time-of-flight mass spectrometry (UPLC/Q-TOF/MS) in ESI⁺ mode: a OPLS-DA score plot. b OPLS-DA loading plot in ESI⁺ mode and variables labeled with retention time. (Black square): DCM model rat, M; (black square): c Control rat, OPLS-DA orthogonal projection to latent structures discriminant analysis, ESI electrospray mode electrospray ionization