2004 | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Antihyperglycemic medication | ||||||||||||
n | 206,015 | 246,453 | 270,251 | 309,867 | 344,343 | 367,046 | 390,126 | 406,919 | 421,065 | 422,019 | 423,640 | 425,342 |
% | 75.7 | 76.4 | 76.4 | 76.4 | 77.6 | 77.2 | 77.1 | 76.4 | 75.5 | 74.7 | 73.8 | 73.3 |
Metformin | ||||||||||||
n | 110,237 | 139,903 | 160,445 | 192,346 | 223,018 | 245,607 | 269,810 | 288,871 | 303,841 | 307,339 | 310,177 | 314,075 |
% | 40.5 | 43.4 | 45.3 | 47.4 | 50.2 | 51.7 | 53.3 | 54.3 | 54.5 | 54.4 | 54.0 | 54.1 |
Insulin | ||||||||||||
n | 67,491 | 79,835 | 88,270 | 100,335 | 108,872 | 113,476 | 117,963 | 121,185 | 125,045 | 126,496 | 128,680 | 131,760 |
% | 24.8 | 24.8 | 24.9 | 24.7 | 24.5 | 23.9 | 23.3 | 22.8 | 22.4 | 22.4 | 22.4 | 22.7 |
Of which | ||||||||||||
Monotherapy | ||||||||||||
n | 37,378 | 42,517 | 45,574 | 50,090 | 51,680 | 51,583 | 51,011 | 50,229 | 49,289 | 47,134 | 45,397 | 44,347 |
% | 55.4 | 53.3 | 51.6 | 49.9 | 47.5 | 45.5 | 43.2 | 41.4 | 39.4 | 37.3 | 35.3 | 33.7 |
With metformin | ||||||||||||
n | 19,182 | 24,691 | 29,586 | 35,946 | 41,452 | 45,734 | 50,160 | 53,992 | 58,085 | 60,871 | 63,473 | 66,900 |
% | 28.4 | 30.9 | 33.5 | 35.8 | 38.1 | 40.3 | 42.5 | 44.6 | 46.5 | 48.1 | 49.3 | 50.8 |