Table 3 Logistic regression analysis for determining the risk factor of developing T2DM
From: Association of the polymorphism in NUCB2 gene and the risk of type 2 diabetes
Characteristics | Model 1 | Model 2 | Model 3 | |||
|---|---|---|---|---|---|---|
OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | |
Age (years) | 1.002 (0.987–1.018) | 0.771 | 1.011 (0.993–1.029) | 0.226 | 0.990 (0.970–1.009) | 0.303 |
Gender (M/F) | 1.102 (0.770–1.577) | 0.594 | 1.555 (1.043–2.320) | 0.030 | 1.714 (1.105–2.658) | 0.016 |
BMI (kg/m2) | 1.039 (0.985–1.095) | 0.157 | 0.997 (0.942–1.056) | 0.926 | 0.979 (0.919–1.042) | 0.506 |
SBP (mmHg) | – | – | – | – | 1.066 (1.047–1.086) | <0.001 |
DBP (mmHg) | – | – | – | – | 0.978 (0.951–1.006) | 0.126 |
TG (mmol/L) | – | – | 0.941 (0.763–1.162) | 0.573 | 0.957 (0.772–1.186) | 0.690 |
TC (mmol/L) | – | – | 3.247 (1.310–8.050) | 0.011 | 2.943 (1.235–7.012) | 0.015 |
HDL (mmol/L) | – | – | 0.025 (0.008–0.078) | <0.001 | 0.032 (0.010–0.099) | <0.001 |
LDL (mmol/L) | – | – | 0.534 (0.211–1.351) | 0.185 | 0.534 (0.222–1.286) | 0.162 |
c.1012C>G polymorphism | 0.704 (0.551–0.899) | 0.005 | 0.768 (0.589–0.989) | 0.042 | 0.773 (0.578–1.032) | 0.081 |