Skip to main content

Table 2 Genotypic distribution of the studied SNPs in controls and GDM patients

From: Gene variants in the FTO gene are associated with adiponectin and TNF-alpha levels in gestational diabetes mellitus

Polymorphisms

Genotype

Control

GDM

OR (95% CI)

P

FTO rs8050136

CC

59 (73.8)

61 (76.3)

1.11 (0.54–2.27)

0.855

CA

20 (25.0)

18 (22.5)

  

AA

1 (1.2)

1 (1.1)

  

Risk allele

A

    

Risk allele frequency (%)

 

13.7

12.4

  

FTO rs9939609

TT

59 (73.8)

61 (76.3)

1.11 (0.54–2.27)

0.855

TA

20 (25.0)

18 (22.5)

  

AA

1 (1.2)

1 (1.1)

  

Risk allele

A

    

Risk allele frequency (%)

 

13.7

12.4

  

FTO rs1421085

TT

58 (72.5)

64 (80.0)

1.54 (0.75–3.2)

0.278

TC

20 (25.0)

15 (18.8)

  

CC

2 (2.5)

1 (1.2)

  

Risk allele

C

    

Risk allele frequency (%)

 

15.0

10.6

  
  1. SNPs single nucleotide polymorphisms, FTO fat mass and obesity associated gene, GDM gestational diabetes mellitus, OR odds ratio, CI confidence interval