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Table 1 Anthropometric and biochemical characteristics at the time of recruitment

From: Gene variants in the FTO gene are associated with adiponectin and TNF-alpha levels in gestational diabetes mellitus

 

Control (n = 80)

GDM (n = 80)

P

Age (years)

24 (18.8–27.3)

33 (28.5–36.0)

<0.001

Pre-pregnancy weight (kg)

55 (49–63)

72 (62.5–79.5)

<0.001

Pre-pregnancy BMI (kg/m2)

23 (21–25)

30 (26.7–32.8)

<0.001

Gestational weight gain (kg)

8 (5.6–10)

6.9 (3–10)

0.256

Family history of diabetes (%)

21 (26.0)

52 (65)

<0.001

Fasting glucose (mg/dL)

67.7 (62.8–74.0)

99 (85.8–121.5)

<0.001

Insulin (μIU/mL)

6.7 (4.5–12)

19.2 (6.9–34.9)

<0.001

HOMA-IR

1.09 (0.72–2.0)

4.1 (1.7–10.4)

<0.001

Total cholesterol (mg/dL)

230.4 (214.9–255.3)

237.1 (215.6–268.7)

0.653

Triglycerides (mg/dL)

220.8 (162.1–285.0)

286.6 (225.4–357.1)

<0.001

Leptin (ng/mL)

19.9 (14.3–29.4)

19 (14.0–23.9)

0.902

Adiponectin (ng/mL)

10.8 (7.9–15.2)

8.4 (6.0–10.7)

0.585

Ghrelin (pg/mL)

598.3 (534.4–701.5)

622.4 (505.3–699.8)

0.745

TNF-alpha (pg/mL)

9.5 (7.9–11.7)

10.3 (9.2–12.4)

0.158

  1. Data are expressed as median (interquartile range 25–75%)
  2. GDM gestational diabetes mellitus, BMI body mass index, HOMA-IR homeostasis model assessment index
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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