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Table 5 Comparison of characteristics and complications between the young- and old-onset T2DM cohorts at last contact

From: Characteristics and cardiovascular complications of a large cohort of adults diagnosed with type 2 diabetes <45 years

  Age at diagnosis <45 years
N = 886
Age at diagnosis 60–70 years
N = 933
p value Adjusted p value
% Men 55.9 53.2 0.246  
% Belgian nationality 91.3 97.2 0.024  
Mean age at last visit (years) 57.3 ± 12.6 75.7 ± 6.8 <0.0001  
Median age at diagnosis (years) 39.0 (8;45) 64.1 (60;70) <0.0001  
Median follow-up (years) 7.6 (0;17) 4.6 (1;17) <0.0001  
Mean diabetes duration (years) 20.5 ± 11.8 11.9 ± 6.6 <0.0001  
Mean HbA1c % (mmol/mol) 7.3 ± 1.3 (56 ± 14) 6.9 ± 1.0 (51 ± 11) <0.0001  
Mean BMI (kg/m2) 31.2 ± 5.8 29.6 ± 5.5 <0.0001  
 % Overweight 32.4 38.3 0.011  
 % Obese 56.8 42.0 <0.0001  
 % Hypertension 49.9 50.2 0.905  
Median TG 118.5 (25;2837) 118.0 (24;706) 0.829  
Mean LDL 77.5 ± 30.9 75.2 ± 29.4 0.163  
 % Smoking 16.6 7.0 <0.0001  
 % DRP 40.2 23.7 <0.0001  
 % Microalbuminuria 34.4 34.0 0.915  
 % Carotid surgery 0.9 (8) 4.3 (40) <0.0001 0.843
 % Surgery lower limbs 6.9 (61) 10.5 (98) 0.006 0.327
 % TIA/CVA 7.2 (64) 16.1 (150) <0.0001 0.739
 % Cardiac event 20.1 (178) 31.8 (297) <0.0001 0.386
  1. Data are mean ± SD or %
  2. p values highlighted in italic are considered significant
  3. BMI body mass index; TG triglycerides; LDL LDL-cholesterol; DRP diabetic retinopathy; TIA transient ischemic attack; CVA cerebrovascular accident; cardiac event a myocardial infarction or an intervention such as a percutaneous transluminal coronary angioplasty or a coronary artery bypass graft