Table 1 Characteristics and complications for men and women at last contact in the young-onset cohort
Men N = 495 (55.9%) | Women N = 391 (44.1%) | p value | |
|---|---|---|---|
% EM | 12.4 | 11.7 | 0.762 |
Mean age at diagnosis | 38.1 ± 5.8 | 36.4 ± 6.9 | <0.0001 |
Mean age at last visit (years) | 56.9 ± 11.5 | 57.8 ± 13.8 | 0.283 |
Mean follow-up (years) | 8.1 ± 4.8 | 8.8 ± 5.1 | 0.029 |
Mean diabetes duration (years) | 19.3 ± 11.0 | 22.0 ± 12.7 | 0.001 |
Mean HbA1c % (mmol/mol) | 7.3 ± 1.4 (56 ± 15) | 7.1 ± 1.2 (54 ± 13) | 0.021 |
% HbA1c ≥9% (74 mmol/mol) | 13.7 | 8.0 | 0.008 |
% Statin | 79.6 | 70.8 | 0.006 |
Number of antihypertensive medications | 0.177 | ||
0 | 21.4 | 25.3 | |
1 | 18.4 | 15.3 | |
2 | 17.6 | 23.0 | |
≥3 | 42.5 | 36.4 | |
% Aspirin | 58.6 | 55.5 | 0.356 |
% MF | 53.1 | 55.5 | 0.483 |
% SU | 1.4 | 1.8 | 0.656 |
% MF + SU | 16.6 | 8.2 | <0.0001 |
% Glitazones | 0.2 | 0.5 | 0.431 |
% DPP-4 | 3.6 | 3.3 | 0.802 |
% GLP-1 | 10.9 | 5.1 | 0.002 |
% Insulin | 79.8 | 84.7 | 0.062 |
% On 1 injection of insulin | 5.3 | 5.6 | 0.807 |
% On 2 or 3 injections of insulin | 5.9 | 8.2 | 0.175 |
% On multiple injections of insulin | 68.7 | 70.8 | 0.488 |
Mean BMI (kg/m2) | 30.5 ± 4.9 | 32.1 ± 6.7 | <0.0001 |
% Overweight | 39.4 | 23.4 | <0.0001 |
% Obese | 51.2 | 64.1 | <0.0001 |
% Hypertension | 53.4 | 45.3 | 0.019 |
Mean TG | 162.9 ± 175.7 | 135.6 ± 78.8 | 0.007 |
Mean LDL | 74.1 ± 30.1 | 81.7 ± 31.2 | <0.0001 |
% High TG | 35.7 | 30.1 | 0.093 |
% LDL not on target in primary CV prevention | 24.8 | 32.4 | 0.065 |
% LDL not on target in secondary CV prevention | 51.1 | 39.9 | 0.052 |
% Smoking | 20.2 | 12.0 | 0.001 |
% ≥3 CV risk factors | 59.4 | 50.1 | 0.006 |
% DRP | 40.3 | 40.1 | 0.942 |
% Microalbuminuria | 40.6 | 26.2 | 0.001 |
Mean age first CV event | 53.4 ± 9.5 | 57.9 ± 10.1 | <0.0001 |
% New surgery lower limbs | 3.0 (15) | 2.0 (8) | |
% New TIA/CVA | 1.0 (5) | 1.0 (4) | |
% New cardiac event | 4.8 (24) | 3.1 (12) |