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Table 3 Character of the study groups regarding, anthropometric, routine biochemical data, inflammatory and oxidative stress markers at the end of the study

From: Effect of variable antidiabetic treatments strategy on oxidative stress markers in obese patients with T2DM

Variables

Group 1

Group 2

Group 3

Group 4

P value

BMI kg/m2

34.64 ± 7.07

32.97 ± 5.53

31.41 ± 3.73

30.73 ± 3.29

0.054

FBG mg/dl

127.8 ± 17.48

126.05 ± 23.31

150.58 ± 10.03

164.85 ± 47.51

0.0001

124 (78)

111.5 (96)

150 (60)

140 (151)

 

PPBG mg/dl

157.2 ± 35.71

179.32 ± 30.01

182.27 ± 8.72

249.5 ± 15.71

0.0001#•

153 (135)

189 (145)

200 (32)

282 (52)

 

HbA1C%

6.77 ± 0.84

7.73 ± 1.17

7.76 ± 0.93

8.85 ± 1.72

0.0001#”

TC mg/dl

172.6 ± 25.42

182.41 ± 36.29

171.08 ± 35.02

174.5 ± 44.31

0.69

TG mg/dl

147.54 ± 59.01

157.66 ± 51.63

166.67 ± 73.01

217 ± 91.26

 

136 (90–290)

143.5 (99–296)

140 (112–400)

208.5 (111–340)

0.02*

LDLc mg/dl

99.28 ± 18.54

93.68 ± 26.66

112.42 ± 28.83

94.15 ± 19.86

0.027

HDLc

43.88 ± 9.47

41.09 ± 7.77

42.46 ± 4.39

32.85 ± 4.74

0.0001#

40 (35)

40 (26)

43.5 (17)

32 (16)

 

LDcL/HDLc

2.37 ± 0.67

2.38 ± 0.88

2.75 ± 1.11

2.92 ± 0.71

0.048

22 (2.4)

2.13 (3.15)

2.47 (4.49)

2.73 (2.33)

 

s.creatinine mg/dl

0.95 ± 0.04

0.95 ± 0.06

0.96 ± 0.06

0.94 ± 0.04

0.56

0.9 (0.84–1.05)

0.97 (0.84–1.09)

0.98 (0.85–1.08)

0.94 (0.85–1)

 

Urea mg/dl

28.70 ± 3.42

27.8 ± 2.36

27.9 ± 1.65

28.35 ± 2.1

0.53

MDA μM

8.4 ± 2.55

8.04 ± 2.72

7.34 ± 1.87

8.7 ± 2.58

0.29

7.1 (8)

8 (10.8)

7 (5.5)

8.5 (7)

 

OxLDLc pg/ml

1135.4 ± 427.5

1063.8 ± 513.64

1277.3 ± 590.4

1263.4 ± 1064.5

0.22

980 (1976)

1011.5 (2030)

1065 (1916)

874 (3206)

 

OxLDLc/LDLc

10.26 ± 3.83

10.16 ± 5.47

11.86 ± 5.55

13.48 ± 12.95

0.54

9.77 (16.67)

9.17 (27.18)

11.83 (17.11)

8.84 (40.5)

 

OxLDLc/HDLc

29.17 ± 16.86

26.32 ± 14.49

32.12 ± 15.91

37.86 ± 36.35

0.39

23.08 (72.83)

21.52 (55.64)

28.05 (49.47)

21.85 (106.44)

 
  1. Italic values indicate analysis of non-parametric data of more than two groups by Kruskal–Wallis test
  2. * Post hoc significance between G1 vs.G2, G3 and G4
  3. Post hoc significance between G3 and G4 vs. G1 and G2
  4. # Post hoc significance between G4 vs. G1, G2 and G3
  5. Post hoc significance between G1 vs. G2 and G3
  6. Post hoc significance between G3 vs. G2