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Table 1 Glycemic status and prevalence of metabolic syndrome according to family history of diabetes in first-degree relatives

From: Increased risk of metabolic disorders in healthy young adults with family history of diabetes: from the Korea National Health and Nutrition Survey

 

Total (n = 2059)

Men (n = 876)

Women (n = 1183)

FH−

FH+

P

FH−

FH+ 

P

FH−

FH+

P

(n = 1570)

(n = 489)

(n = 655)

(n = 221)

(n = 915)

(n = 268)

Glycemic status

NGT

1358 (86.5%)

386 (78.9%)

<0.001

533 (81.4%)

158 (71.5%)

<0.001

825 (90.2%)

228 (85.1%)

0.019

IFG

184 (11.7%)

70 (14.3%)

 

111 (16.9%)

42 (19.0%)

 

73 (8.0%)

28 (10.4%)

 

Diabetes

28 (1.8%)

33 (6.7%)

 

11 (1.7%)

21 (9.5%)

 

17 (1.9%)

12 (4.5%)

 

Prevalence of metabolic syndrome

190 (12.1%)

104 (21.3%)

<0.001

123 (18.8%)

74 (33.5%)

<0.001

67 (7.3%)

30 (11.2%)

0.042

Waist circumference (>90 cm in men and >80 cm in women)

344 (22.1%)

131 (26.9%)

0.029

144 (22.1%)

58 (26.5%)

0.186

200 (22.1%)

73 (27.2%)

0.082

Triglycerides (≥150 mg/dL or medication use)

323 (20.6%)

146 (29.9%)

<0.001

236 (36.1%)

105 (47.5%)

0.003

87 (9.5%)

41 (15.3%)

0.010

HDL cholesterol (<40 mg/dL in men and <50 mg/dL in women or medication use)

583 (37.2%)

200 (40.9%)

0.142

205 (31.3%)

83 (37.6%)

0.089

378 (41.4%)

117 (43.7%)

0.511

Blood pressure (≥130/85 mmHg or antihypertensive medication use)

222 (14.1%)

100 (20.4%)

0.001

162 (24.7%)

83 (37.6%)

<0.001

60 (6.6%)

17 (6.3%)

0.901

Fasting glucose (≥100 mg/dL or medication use)

212 (13.5%)

103 (21.1%)

<0.001

122 (18.6%)

63 (28.5%)

0.002

90 (9.8%)

40 (14.9%)

0.019

  1. Statistical significance was defined as a P value of <0.05 (Italic values)
  2. FH family history of diabetes, IFG impaired fasting glucose, NGT normal glucose tolerance
  3. P values are from χ2-test