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Table 1 Characteristic of subjects

From: C-peptide is independent associated with diabetic peripheral neuropathy: a community-based study

 

Non-DPN (128)

P 1V3

Clinically-DPN (35)

P 1V2

Comfirmed DPN (57)

P 2V3

Age (year)

62.3 ± 8.4

0.449

63.3 ± 10.7

0.527

64.5 ± 8.8

0.726

Sex (male %)

41%

0.568

58.40%

0.634

46%

0.62

Diabetes duration (year)

8.5 ± 7.2

0.084

9.7 ± 7.7

0.435

12.6 ± 6.9

0.228

Smoking

12 (9.4%)

0.736

4 (11.4%)

0.543

6 (10.5) %

0.612

BMI (kg/cm2)

25.1 ± 3.8

0.393

25.8 ± 4.7

0.421

26.9 ± 1.3

0.167

SBP (mmHg)

133 ± 16

0.036

135 ± 16

0.501

141 ± 13

0.056

DBP (mmHg)

78 ± 8

0.239

77 ± 11

0.431

83 ± 9

0.068

FPG (mmol/L)

8.40 ± 2.43

0.033

8.89 ± 2.33

0.523

9.37 ± 2.60

0.465

2 h-PG (mmol/L)

15.79 ± 4.81

0.012

16.47 ± 4.63

0.607

18.14 ± 4.81

0.263

TC (mmol/L)

5.30 ± 1.02

0.356

5.19 ± 1.06

0.737

5.10 ± 1.26

0.823

TG (mmol/L)

2.11 ± 1.17

0.742

2.38 ± 0.82

0.448

2.05 ± 1.12

0.383

HDL-C (mmol/L)

1.33 ± 0.45

0.018

1.18 ± 0.18

0.217

1.14 ± 0.22

0.788

LDL-C (mmol/L)

2.96 ± 0.77

0.906

3.02 ± 0.83

0.804

2.98 ± 1.09

0.878

HBA1c (%)

7.4 ± 1.4

0.007

7.6 ± 1.4

0.929

8.5 ± 1.9

0.229

GA (%)

18.7 ± 3.7

0.091

20.4 ± 5.2

0.417

22.8 ± 6.1

0.086

Cr (μmol/L)

61.54 ± 15.35

0.276

63.94 ± 17.11

0.63

67.6 ± 17.30

0.278

eGFR (mL/min/1.73 m2)

104.35 ± 31.32

0.857

106.34 ± 26.13

0.826

105.45 ± 30.86

0.93

Median MNCV

53.7 ± 3.1

<0.001

51.2 ± 5.7

0.033

46.5 ± 3.4

0.005

Median MNCA

8.9 ± 2.3

0.014

7.8 ± 2.8

0.398

6.9 ± 2.4

0.516

Median SNCV

51.8 ± 8.6

0.001

48.7 ± 8.8

0.086

41.9 ± 8.3

0.028

Median SNCA

21.4 ± 6.8

<0.001

17.0 ± 8.2

0.03

9.6 ± 5.4

<0.001

Tibial MNCV

44.5 ± 3.2

0.012

40.8 ± 5.89

0.007

35.8 ± 6.0

0.15

Tibial MNCA

8.7 ± 3.1

<0.001

8.2 ± 3.7

0.649

5.2 ± 3.5

0.02

Sural SNCV

50.3 ± 8.5

<0.001

47.5 ± 6.3

0.114

36.3 ± 3.9

0.002

Sural SNCA

13.2 ± 5.6

<0.001

10.4 ± 3.2

0.114

6.1 ± 3.1

<0.001

Insulin

16 (12.5%)

0.347

7 (20%)

0.576

13 (22.4%)

0.747

Sulfonylureas

32 (25.0%)

0.415

10 (28.6%)

0.589

21 (36.8%)

0.467

Metformin

46 (35.9%)

0.423

14 (40%)

0.71

25 (43.8%)

0.745

ACEI or ARB

33 (25.8%)

0.768

12 (34.3%)

0.896

19 (33.3%)

0.824

  1. Results expressed as mean (standard deviation) or percentage
  2. DPN diabetic peripheral neuropathy, BMI body mass index, DBP diastolic blood pressure, SBP systolic blood pressure, FPG fasting plasma glucose, 2 h-PG 2 h-postprandial glucose, TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, HbA1c glycosylated hemoglobin A1c, GA glycated albumin, Cr serum creatinine, eGFR estimated glomerular filtration rate, MNCV motor nerve conduction velocity, MNCA motor nerve conduction amplitude, SNCV sensory nerve conduction velocity, SNCA sensory nerve conduction amplitude, ACEI angiotensin-converting enzyme inhibitors, ARB, angiotensin receptor blocker, P 1V3 non-DPN versus confirmed DPN, P 1V2 non-DPN versus clinical DPN, P 2V3 clinical DPN versus confirmed DPN
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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