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Table 1 Baseline characteristics and laboratory data of the studied population

From: CML/RAGE signal induces calcification cascade in diabetes

Variables Mild stenosis Moderate stenosis Severe stenosis/occlusion
Males/females 9/6 8/7 8/7
Age (years) 65 ± 9 67 ± 8 71 ± 10
Diabetes duration (years) 10 ± 4 11 ± 5 12 ± 7
Hypertension (%) 67 67 73
Smoking (%) 33 40 33
FPG (mg/dL) 120.61 ± 13.53 130.87 ± 9.81 138.85 ± 15.80
HbA1c (%) 7.50 ± 1.62 9.31 ± 2.43* 12.33 ± 2.79*,#
Total cholesterol (mg/dL) 190.75 ± 32.58 188.51 ± 29.83 208.79 ± 48.13
Triglycerides (mg/dL) 172.51 ± 20.55 181.54 ± 18.73 192.81 ± 21.93
LDL-cholesterol (mg/dL) 142.61 ± 15.93 138.71 ± 12.89 158.71 ± 18.93
HDL-cholesterol (mg/dL) 40.51 ± 7.57 37.95 ± 6.17 41.21 ± 9.73
BUN (mmol/L) 6.03 ± 1.12 6.81 ± 0.73 6.92 ± 1.09
SCr (μmol/L) 103.51 ± 11.92 123.67 ± 8.83 131.54 ± 12.86
CML(ng/mL) 28.71 ± 4.81 36.80 ± 5.23* 57.66 ± 6.47*,#
  1. Values are expressed as number (%) or mean ± SD, n = 15 for each group
  2. FPG fasting plasma glucose, HbA1c glycated hemoglobin, LDL low density lipoprotein, HDL high density lipoprotein, BUN blood urea nitrogen, SCr serum creatinine, CML Nε-carboxymethyl-lysine
  3. P < 0.05, compared with the mild stenosis group
  4. # P < 0.05, compared with the moderate stenosis group