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Table 1 Baseline characteristics and laboratory data of the studied population

From: CML/RAGE signal induces calcification cascade in diabetes

Variables

Mild stenosis

Moderate stenosis

Severe stenosis/occlusion

Males/females

9/6

8/7

8/7

Age (years)

65 ± 9

67 ± 8

71 ± 10

Diabetes duration (years)

10 ± 4

11 ± 5

12 ± 7

Hypertension (%)

67

67

73

Smoking (%)

33

40

33

FPG (mg/dL)

120.61 ± 13.53

130.87 ± 9.81

138.85 ± 15.80

HbA1c (%)

7.50 ± 1.62

9.31 ± 2.43*

12.33 ± 2.79*,#

Total cholesterol (mg/dL)

190.75 ± 32.58

188.51 ± 29.83

208.79 ± 48.13

Triglycerides (mg/dL)

172.51 ± 20.55

181.54 ± 18.73

192.81 ± 21.93

LDL-cholesterol (mg/dL)

142.61 ± 15.93

138.71 ± 12.89

158.71 ± 18.93

HDL-cholesterol (mg/dL)

40.51 ± 7.57

37.95 ± 6.17

41.21 ± 9.73

BUN (mmol/L)

6.03 ± 1.12

6.81 ± 0.73

6.92 ± 1.09

SCr (μmol/L)

103.51 ± 11.92

123.67 ± 8.83

131.54 ± 12.86

CML(ng/mL)

28.71 ± 4.81

36.80 ± 5.23*

57.66 ± 6.47*,#

  1. Values are expressed as number (%) or mean ± SD, n = 15 for each group
  2. FPG fasting plasma glucose, HbA1c glycated hemoglobin, LDL low density lipoprotein, HDL high density lipoprotein, BUN blood urea nitrogen, SCr serum creatinine, CML Nε-carboxymethyl-lysine
  3. P < 0.05, compared with the mild stenosis group
  4. # P < 0.05, compared with the moderate stenosis group