Fig. 5

Intragastric administration of 3DG for 2 weeks caused normal rats to develop increased fasting blood glucose concentration and impaired oral glucose tolerance n = 6 for each group. a Fasting plasma glucose levels were measured in rats after 2 weeks of 3DG (5, 20, 50 mg/kg) or vehicle treated. b OGTT (2.5 g/kg) was performed after 2-week administration of 3DG (5, 20, 50 mg/kg) or vehicle in rats. c The glycaemic response was expressed as the area under the curve. Values are mean ± SD. ^# p < 0.05, ^## p < 0.01 ^### p < 0.001 compared with control group at the same point (b). *p < 0.05, ***p < 0.001 compared with control group (a, c)