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Fig. 5 | Diabetology & Metabolic Syndrome

Fig. 5

From: Accumulation of intestinal tissue 3-deoxyglucosone attenuated GLP-1 secretion and its insulinotropic effect in rats

Fig. 5

Intragastric administration of 3DG for 2 weeks caused normal rats to develop increased fasting blood glucose concentration and impaired oral glucose tolerance n = 6 for each group. a Fasting plasma glucose levels were measured in rats after 2 weeks of 3DG (5, 20, 50 mg/kg) or vehicle treated. b OGTT (2.5 g/kg) was performed after 2-week administration of 3DG (5, 20, 50 mg/kg) or vehicle in rats. c The glycaemic response was expressed as the area under the curve. Values are mean ± SD. # p < 0.05, ## p < 0.01 ### p < 0.001 compared with control group at the same point (b). *p < 0.05, ***p < 0.001 compared with control group (a, c)

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