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Fig. 4 | Diabetology & Metabolic Syndrome

Fig. 4

From: Accumulation of intestinal tissue 3-deoxyglucosone attenuated GLP-1 secretion and its insulinotropic effect in rats

Fig. 4

Reduced plasma insulin concentrations and elevated plasma glucagon concentrations in rats 2 weeks after intragastric administration of 3DG, n = 6 for each group. Plasma insulin concentrations (a) and glucagon concentrations (b) were measured before and after oral glucose load (2.5 g/kg) in 3DG (5, 20, 50 mg/kg) or vehicle-treated rats for 2 weeks. Values are mean ± SD. # p < 0.05, # p < 0.01 ### p < 0.001 compared with control group at the same point (a, b). *p < 0.05, ***p < 0.001 compared with control group (a, b)

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