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Table 2 Summary of findings on skin alterations in DM patients

From: Skin disorders in diabetes mellitus: an epidemiology and physiopathology review

Parameter

Effect in DM patients

Reference

Hydration

Decreased

Sakai et al. [30]

No alteration

Seirafi et al. [31]

Trans-epidermal loss

Not altered

Sakai et al. [30]

Seirafi et al. [31]

Filaggrin

Alteration

Thyssen et al. [32]

Other possible signs of barrier defect

Increased inflammatory infiltration

Tellechea et al. [33]

Epidermal thickness

No alteration

Zakharov et al. [29]

Thicker epidermis

Bertheim et al. [28]

  1. Adapted from Quondamatteo [2]