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Table 3 Indices for glycemic variability for every 6-h segment over 24 h in all HbA1c subgroups

From: The relationship between HbA1c values and the occurrence of hypoglycemia as assessed by continuous glucose monitoring in patients with type 1 diabetes

HbA1c

Group A

HbA1c ≤7.2 %

Group B

7.2 % <HbA1c ≤8.2 %

Group C

8.2 % <HbA1c ≤9.2 %

Group D

HbA1c >9.2 %

P value

0 a.m.–6 a.m.

Mean glucose levels (mg/dL)

86.5

(66.9–117.2)

99.8

(85.6–144.1)

135.0

(82.0–165.8)

127.2

(84.2–197.4)

0.020

6 a.m.–12 noon

Mean glucose levels (mg/dL)

158.3

(132.8–208.6)

176.3

(145.5–224.1)

188.5

(153.5–251.1)

174.5

(143.7–237.1)

0.105

12 noon–18 p.m.

Mean glucose levels (mg/dL)

127.3

(108.9–149.6)

133.3

(120.6–190.9)

190.5

(146.4–247.8)

177.4

(120.7–250.3)

0.007

18 p.m.–12 midnight

Mean glucose levels (mg/dL)

156.8

(110.1–195.8)

161.5

(126.1–234.8)

194.2

(150.1–245.2)

210.2

(139.3–234.9)

0.013

0 a.m.–6 a.m.

SD (mg/dL)

19.6

(10.8–25.3)

18.2

(11.5–30.2)

20.6

(13.4–31.8)

23.0

(13.3–36.4)

0.402

6 a.m.–12 noon

SD (mg/dL)

37.7

(28.4–59.2)

40.2

(32.7–63.9)

40.5

(35.8–68.0)

47.1

(30.7–57.2)

0.604

12 noon–18 p.m.

SD (mg/dL)

29.6

(18.1–41.2)

27.7

(18.8–41.7)

30.4

(21.6–51.7)

33.5

(26.6–48.0)

0.446

18 p.m.–12 midnight

SD (mg/dL)

35.5

(22.5–44.9)

33.8

(28.3–51.5)

35.6

(24.3–43.6)

36.7

(25.2–54.1)

0.891

0 a.m.–6 a.m.

% CV

22.6

(14.1–33.3)

19.5

(10.6–25.1)

17.9

(12.8–27.3)

17.2

(11.8–26.9)

0.608

6 a.m.–12 noon

% CV

26.3

(15.2–35.7)

23.7

(18.3–30.9)

23.5

(18.5–30.7)

25.0

(17.6–33.5)

0.978

12 noon–18 p.m.

% CV

17.9

(14.6–35.7)

20.0

(16.1–27.0)

18.1

(11.1–28.2)

19.9

(13.3–29.6)

0.905

18 p.m.–12 midnight

% CV

23.6

(16.9–28.0)

21.9

(17.3–27.4)

17.8

(12.2–23.2)

21.0

(11.5–25.3)

0.136

  1. Data presented as median (25–75 percentiles)
  2. Italic values indicate significance of P value (P < 0.05)
  3. aKruskal–Wallis test