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Table 3 Indices for glycemic variability for every 6-h segment over 24 h in all HbA1c subgroups

From: The relationship between HbA1c values and the occurrence of hypoglycemia as assessed by continuous glucose monitoring in patients with type 1 diabetes

HbA1c Group A
HbA1c ≤7.2 %
Group B
7.2 % <HbA1c ≤8.2 %
Group C
8.2 % <HbA1c ≤9.2 %
Group D
HbA1c >9.2 %
P value
0 a.m.–6 a.m.
Mean glucose levels (mg/dL)
86.5
(66.9–117.2)
99.8
(85.6–144.1)
135.0
(82.0–165.8)
127.2
(84.2–197.4)
0.020
6 a.m.–12 noon
Mean glucose levels (mg/dL)
158.3
(132.8–208.6)
176.3
(145.5–224.1)
188.5
(153.5–251.1)
174.5
(143.7–237.1)
0.105
12 noon–18 p.m.
Mean glucose levels (mg/dL)
127.3
(108.9–149.6)
133.3
(120.6–190.9)
190.5
(146.4–247.8)
177.4
(120.7–250.3)
0.007
18 p.m.–12 midnight
Mean glucose levels (mg/dL)
156.8
(110.1–195.8)
161.5
(126.1–234.8)
194.2
(150.1–245.2)
210.2
(139.3–234.9)
0.013
0 a.m.–6 a.m.
SD (mg/dL)
19.6
(10.8–25.3)
18.2
(11.5–30.2)
20.6
(13.4–31.8)
23.0
(13.3–36.4)
0.402
6 a.m.–12 noon
SD (mg/dL)
37.7
(28.4–59.2)
40.2
(32.7–63.9)
40.5
(35.8–68.0)
47.1
(30.7–57.2)
0.604
12 noon–18 p.m.
SD (mg/dL)
29.6
(18.1–41.2)
27.7
(18.8–41.7)
30.4
(21.6–51.7)
33.5
(26.6–48.0)
0.446
18 p.m.–12 midnight
SD (mg/dL)
35.5
(22.5–44.9)
33.8
(28.3–51.5)
35.6
(24.3–43.6)
36.7
(25.2–54.1)
0.891
0 a.m.–6 a.m.
% CV
22.6
(14.1–33.3)
19.5
(10.6–25.1)
17.9
(12.8–27.3)
17.2
(11.8–26.9)
0.608
6 a.m.–12 noon
% CV
26.3
(15.2–35.7)
23.7
(18.3–30.9)
23.5
(18.5–30.7)
25.0
(17.6–33.5)
0.978
12 noon–18 p.m.
% CV
17.9
(14.6–35.7)
20.0
(16.1–27.0)
18.1
(11.1–28.2)
19.9
(13.3–29.6)
0.905
18 p.m.–12 midnight
% CV
23.6
(16.9–28.0)
21.9
(17.3–27.4)
17.8
(12.2–23.2)
21.0
(11.5–25.3)
0.136
  1. Data presented as median (25–75 percentiles)
  2. Italic values indicate significance of P value (P < 0.05)
  3. aKruskal–Wallis test