Clinical consequence | T1DMÂ +Â CD | Patients on GFD | References |
---|---|---|---|
HbA1c | Hba1c in screen detected CD patients is lower (Kaukinen, Bakker), higher (Leeds) | NA | [50] |
NA | [51] | ||
NA | [59] | ||
No difference in HbA1c during follow up | Yes | [51] | |
Yes | [54] | ||
No increased risk for hospital admission due to hypoglycaemia, keto-acidosis or coma | Unknown | [52] | |
Cholesterol + triglycerides | Lower in screen detected CD patients | NA | [59] |
NA | [54] | ||
Nephropathy | Higher prevalence of nephropathy | Unknown | [65] |
Unknown | [64] | ||
Retinopathy | <10Â years of CD results in less retinopathy, more than 10Â years leads to more retinopathy | Unknown | [60] |
Yes | [51] | ||
Bone mineral density | Lower BMD at diagnosis | NA | [71] |
Quality of life | Decrease, particularly in women, both social functioning and general health perception are affected | Yes | [75] |
Depression | Increased risk | Unknown | [77] |
Refractory Coeliac disease | ? | Â | ? |
Enteropathy associated T cell lymphoma | ? | Â | ? |
Mortality | A diagnosis of CD for >15Â years increases the risk of death in patients with T1D | Unknown | [82] |