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Table 3 Insulin pharmacokinetic profiles

From: Interactions between kidney disease and diabetes: dangerous liaisons

Insulin type Onset Peak Duration of action
Rapid-acting profile
Regular 30 min 2–4 h 5–7 h
Short-acting profile
Lispro
Aspart
Glulisine
5–15 min 60–90 min 3–4 h
intermediate-acting profile
NPH* 2 h 6–10 h 13–20 h
Long-acting profile
Glargin ~2 h Flat 20–24 h
Detemir ~2 h Less-pronounced peak 6–24 h
Ultra-long-acting profile
Degludec 20–40 min Flat ~42 h