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Table 1 The clinical baseline characteristics of individuals

From: A study for association and interaction analysis to metabolic syndrome and the ESR1 gene on cardiovascular autonomic neuropathy in a Chinese Han population

Variable

non-MetS

MetS

Entire sample

p value*

Demographical information

N

1194

783

1977

 

Age years

59.8 ± 8.85

61.56 ± 8.37

60.5 ± 8.71

<0.001

Gender male, %

409 (34.25 %)

258 (32.95 %)

667 (33.74 %)

0.396

Height cm

161.5 ± 7.89

161.48 ± 7.79

161.49 ± 7.85

0.942

Weight kg

60.41 ± 9.78

67.69 ± 10.5

63.3 ± 10.68

<0.001

SBP mmHg

122.61 ± 17.33

135.52 ± 18.34

127.71 ± 18.82

<0.001

DBP mmHg

77.82 ± 9.38

82.8 ± 9.38

79.79 ± 9.69

<0.001

Medical history, %

Smoking yes

182 (15.24 %)

122 (15.58 %)

304 (15.38 %)

0.773

HTN yes

371 (31.07 %)

557 (71.14 %)

928 (46.94 %)

<0.001

DM yes

112 (9.39 %)

307 (39.21 %)

419 (21.2 %)

<0.001

CAN yes

173 (14.49 %)

190 (24.27 %)

363 (18.36 %)

<0.001

Laboratory assays 

FPG mmol/L

5.01 ± 1.27

6.19 ± 2.16

5.48 ± 1.78

<0.001

PBG mmol/L

6.63 ± 2.87

9.08 ± 4.02

7.6 ± 3.58

<0.001

FINS uml/L

6.07 ± 10.53

9.07 ± 14.08

7.26 ± 12.16

<0.001

TC mmol/L

5.31 ± 0.96

5.33 ± 1.07

5.32 ± 1

0.603

TG mmol/L

1.35 ± 0.66

2.26 ± 1.14

1.71 ± 0.99

<0.001

HDL mmol/L

1.46 ± 0.32

1.2 ± 0.26

1.36 ± 0.33

<0.001

LDL mmol/L

3.18 ± 0.76

3.21 ± 0.8

3.19 ± 0.78

0.212

SCr μmol/L

76.56 ± 28.72

79.14 ± 22.9

77.58 ± 26.59

0.003

UA μmol/L

265.96 ± 78.37

302.66 ± 87.82

280.51 ± 84.17

<0.001

HRV indices

HR bpm

71.57 ± 9.92

73.96 ± 10.34

72.52 ± 10.16

<0.001

TP ms2

938.73 ± 728.92

788.78 ± 668.07

879.34 ± 709.16

<0.001

LF ms2

210.37 ± 219.54

164.72 ± 189.4

192.29 ± 209.3

<0.001

HF ms2

203.82 ± 241.68

155.52 ± 183.24

184.69 ± 221.63

<0.001

LF/HF

1.67 ± 2.05

1.74 ± 1.87

1.7 ± 1.98

0.307

SNP

rs9340799

237 (19.97 %)

147 (19.08 %)

384 (19.62 %)

0.495

  1. * Difference analysis between non-MetS and MetS groups
  2. SBP systolic blood pressure, DBP diastolic blood pressure, FPG fasting plasma glucose, PBG plasma blood glucose, FINS fasting blood insulin, TC serum total cholesterol, TG triglyceride, UA uric acid, HDL high-density lipoprotein cholesterol, LDL low density lipoprotein cholesterol, SCr serum creatinine, UA uric acid, HR heart rate, TP total power of variance, LF low frequency, HF high frequency, HTN hypertension, MetS metabolic syndrome, DM diabetes mellitus, CAN cardiovascular autonomic neuropathy, SNP single nucleotide polymorphism