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Table 1 The clinical baseline characteristics of individuals

From: A study for association and interaction analysis to metabolic syndrome and the ESR1 gene on cardiovascular autonomic neuropathy in a Chinese Han population

Variable non-MetS MetS Entire sample p value*
Demographical information
N 1194 783 1977  
Age years 59.8 ± 8.85 61.56 ± 8.37 60.5 ± 8.71 <0.001
Gender male, % 409 (34.25 %) 258 (32.95 %) 667 (33.74 %) 0.396
Height cm 161.5 ± 7.89 161.48 ± 7.79 161.49 ± 7.85 0.942
Weight kg 60.41 ± 9.78 67.69 ± 10.5 63.3 ± 10.68 <0.001
SBP mmHg 122.61 ± 17.33 135.52 ± 18.34 127.71 ± 18.82 <0.001
DBP mmHg 77.82 ± 9.38 82.8 ± 9.38 79.79 ± 9.69 <0.001
Medical history, %
Smoking yes 182 (15.24 %) 122 (15.58 %) 304 (15.38 %) 0.773
HTN yes 371 (31.07 %) 557 (71.14 %) 928 (46.94 %) <0.001
DM yes 112 (9.39 %) 307 (39.21 %) 419 (21.2 %) <0.001
CAN yes 173 (14.49 %) 190 (24.27 %) 363 (18.36 %) <0.001
Laboratory assays 
FPG mmol/L 5.01 ± 1.27 6.19 ± 2.16 5.48 ± 1.78 <0.001
PBG mmol/L 6.63 ± 2.87 9.08 ± 4.02 7.6 ± 3.58 <0.001
FINS uml/L 6.07 ± 10.53 9.07 ± 14.08 7.26 ± 12.16 <0.001
TC mmol/L 5.31 ± 0.96 5.33 ± 1.07 5.32 ± 1 0.603
TG mmol/L 1.35 ± 0.66 2.26 ± 1.14 1.71 ± 0.99 <0.001
HDL mmol/L 1.46 ± 0.32 1.2 ± 0.26 1.36 ± 0.33 <0.001
LDL mmol/L 3.18 ± 0.76 3.21 ± 0.8 3.19 ± 0.78 0.212
SCr μmol/L 76.56 ± 28.72 79.14 ± 22.9 77.58 ± 26.59 0.003
UA μmol/L 265.96 ± 78.37 302.66 ± 87.82 280.51 ± 84.17 <0.001
HRV indices
HR bpm 71.57 ± 9.92 73.96 ± 10.34 72.52 ± 10.16 <0.001
TP ms2 938.73 ± 728.92 788.78 ± 668.07 879.34 ± 709.16 <0.001
LF ms2 210.37 ± 219.54 164.72 ± 189.4 192.29 ± 209.3 <0.001
HF ms2 203.82 ± 241.68 155.52 ± 183.24 184.69 ± 221.63 <0.001
LF/HF 1.67 ± 2.05 1.74 ± 1.87 1.7 ± 1.98 0.307
SNP
rs9340799 237 (19.97 %) 147 (19.08 %) 384 (19.62 %) 0.495
  1. * Difference analysis between non-MetS and MetS groups
  2. SBP systolic blood pressure, DBP diastolic blood pressure, FPG fasting plasma glucose, PBG plasma blood glucose, FINS fasting blood insulin, TC serum total cholesterol, TG triglyceride, UA uric acid, HDL high-density lipoprotein cholesterol, LDL low density lipoprotein cholesterol, SCr serum creatinine, UA uric acid, HR heart rate, TP total power of variance, LF low frequency, HF high frequency, HTN hypertension, MetS metabolic syndrome, DM diabetes mellitus, CAN cardiovascular autonomic neuropathy, SNP single nucleotide polymorphism