Outcome

Effect estimate

95 % Confidence limits

p value

Effect estimate

95 % Confidence limits

p value


Lower

Upper

Lower

Upper


Short (<10 years) duration of diabetes

Long (≥10 years) duration of diabetes


Change in HbA1c (%)

−1.28

−1.65

−0.91

<0.0001

−0.93

−1.18

−0.67

<0.0001

Change in weight (kg)

−0.56

−1.34

0.21

0.16

−0.09

−0.66

0.47

0.75

Change in FPG (mg/dL)

−12.7

−26.6

1.2

0.07

−12.6

−24.9

−0.4

0.0438

Change in PPG: meal test (mg/dL)

−152.6

−182.0

−123.2

<0.0001

−147.9

−176.8

−119.0

<0.0001


Odds ratio

95 % Confidence limits

p value

Odds ratio

95 % Confidence limits

p value


Lower

Upper

Lower

Upper


Short (<10 years) duration of diabetes

Long (≥10 years) duration of diabetes


Symptomatic hypoglycemia

5.2

1.5

18.7

0.0107

2.1

0.8

5.2

0.11

Severe hypoglycemia

0.0

0.0

0.0

–

0.0

0.0

0.0

–

Endpoint HbA1c <7 %

32.1

4.2

246.6

0.0009

8.9

2.5

31.9

0.0008

Endpoint HbA1c <7 % and no weight gain

22.5

2.9

174.3

0.0028

6.3

1.7

23.3

0.0057

Endpoint HbA1c <7 % and no symptomatic hypoglycemia

19.8

2.6

153.5

0.0043

9.0

2.0

41.1

0.0046

Endpoint HbA1c <7 % and no weight gain and no symptomatic hypoglycemia

11.6

1.4

93.3

0.0213

7.5

1.6

34.7

0.0099


FPG fasting plasma glucose, PPG postprandial glucose