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Table 2 Laboratory findings of patients with BSCL

From: Clinical and laboratory data of a large series of patients with congenital generalized lipodystrophy

Test

Result

Reference range

Glycemia (mg/dl)

89 (55–424)

70–99

 Non diabetic

71 (55–86)

 Diabetic

152 (67–424)

Glycated hemoglobin (%)

7.4 ± 2.1

<5.7

 Non diabetic

5.4 ± 0.7

 Diabetic

8.3 ± 1.9

Total cholesterol (mg/dl)

170 (106–316)

<200

HDL cholesterol (mg/dl)

30.3 (18–44)

>40 (>50)

LDL cholesterol (mg/dl)

98.6 ± 40.6

Non HDL cholesterol (mg/dl)

147.9 ± 43

Triglyceridemia (mg/dl)

276 (119–1121)

<150

 Non diabetic

190.5 (124–422)

 Diabetic

330 (119–1121)

Urea (mg/dl)

26 (10–74)

15–45

Creatinine (mg/dl)

0.5 (0.3–1.4)

0.6–1.2

AST (mg/dl)

31 (13–98)

<40

ALT (mg/dl)

35 (10–210)

<40

GGT (mg/dl)

31.5 (11–552)

 

 Women

35 (11–552)

<38

 Men

24 (14–114)

<55

Insulin (mUI/ml)

25.8 (2.0–164.0)

<16

 Patients <10 years

11.0 (2.0–41.0)

 

 Patients >10 years

27.8 (4.9–164.0)

 

HOMAIR

7.3 (0.3–73.8)

<2.7

Leptin (ng/ml)

1.0 (0.4–2.3)

 

 Women

1.0 (0.4–2.3)

<14.7

 Men

0.9 (0.5–1.7)

<7.4

  1. All comparisons between non-diabetics and diabetics have p < 0.05
  2. AST aspartate aminotransferase; ALT alanine aminotransferase; GGT gamma-glutamyl transpeptidase; HOMA homeostasis model assessment