Fig. 6From: DPP-4 inhibition improves early mortality, β cell function, and adipose tissue inflammation in db/db mice fed a diet containing sucrose and linoleic acidInflamed adipose tissue was improved by DPP-4 inhibition in db/db mice fed an SL or SO diet. The experiments were performed in 14-week-old mice, as shown in Fig. 2. a Representative histogram of adipocyte size in epididymal fat. b Average size of adipocyte from indicated mice (n = 5). c Epididymal fat tissue was stained with anti-F4/80 antibody. d The number of F4/80+ crown-like structures (CLSs) was counted as described in the Methods (n = 5). *P < 0.05 vs. db/db SL. †P < 0.05 vs. db/db SO. e, f Assessment of the levels of expression of the indicated mRNAs in epididymal fat as determined using real-time quantitative RT-PCR and normalization to the β-actin mRNA level (n = 5). *P < 0.05 vs. db/db SL. †P < 0.05 vs. db/db SOBack to article page