Table 1 Participant characteristics in the full analysis set

Male/female (number, %)

49/19 (72.1/27.9 %)

49/16 (75.4/24.6 %)

Age (year)

64 (8)

63 (9)

BMI (kg/m²)

24.7 (3.3)

24.1 (3.8)

Duration (year)

6.0 (5.1)

6.2 (6.0)

HbA1c (NGSP, %)

7.5 (0.5)

7.4 (0.5)

GA (%)

19.5 (2.8)

19.4 (2.7)

eGFR (ml/min/1.73 m²)

74.9 (14.0)

76.2 (17.1)

ISI (l²/mmol pmol)

16.2 (9.2, 24.0)

16.3 (10.2, 22.0)

Log transformed insulinogenic index (pmol/mmol)

2.6 (2.1, 3.3)

2.2 (1.9, 2.8)

Starting dose (mg/day)

0.25 (20.6 %)

25 (12.3 %)

0.5 (77.9 %)

50 (87.7 %)

1.0 (1.5 %)

100 (0.0 %)