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Table 3 Adjusted logistic regression models , according to presence of insulin resistance [OW(−)IR(+)] or absence [OW(+)IR(−)]

From: Comparison of adipokines in a cross-sectional study with healthy overweight, insulin-sensitive and healthy lean, insulin-resistant subjects, assisted by a family doctor primary care program

 

Model 1

Model 2

Model 3

Model 4

 

OR (95 %)

OR (95 %)

OR (95 %)

OR (95 %)

Age

1.083 (0.925–1.268)

1.064 (0.940–1.205)

0.921 (0.858–0.989)*

1.049 (0.898–1.225)

MCP-1a

1.005 (1.001–1.008)**

1.005 (1.001–1.010)*

1.003 (0.999–1.006)

1.006 (1.001–1.011)*

C reactive protein

–

0.989 (0.979–1.000)*

0.984 (0.966–1.003)

0.992 (0.976–1.008)

IL-6b

1.263 (1.029–1.551)*

1.361 (1.060–1.747)*

1.393 (1.133–1.713)**

1.390 (1.106–1.746)**

Resistin

–

1.016 (1.000–1.033)

1.017 (1.010–1.025)**

1.015 (0.997–1.034)

PAI-1c

–

0.993 (0.976–1.009)

0.981 (0.966–0.997)*

0.985 (0.961–1.011)

Adiponectin

0.893 (0.804–0.991)*

0.868 (0.727–1.037)

1.012 (0.978–1.048)

0.919 (0.741–1.139)

Waist circumf

0.653 (0.471–0.905)*

0.676 (0.514–0.888)**

–

0.693 (0.532–0.903)**

Glycated Hb

1.978 (0.813–4.814)

–

3.332 (1.079–10.293)*

2.575 (0.481–13.801)

White

0.457 (0.089–2.274)

–

–

–

Mulatto or black

1

–

–

–

  1. Binary logistic model adjusted by GEE-In model 1, the variables included were that reached p value <0.150 on parametric and non-parametric tests (Tables 1 and 2). In model 2, all cytokines and a variable related to overweight were included. In model 3, all cytokines and a variable related to glucose metabolic imbalance were included, and waist circumference was excluded. In model 4, all cytokines, a variable related to glucose metabolic imbalance and a variable related to overweight were included
  2. a Macrophage Chemoattractant Protein-1
  3. b Interleukin-6
  4. c Plasminogen activator inhibitor-1
  5. * p value <0.050
  6. ** p value <0.010
  7. Statistical significance was considered as p < 0.05 (in italics)