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Table 2 Genotype distribution of rs1888747 polymorphism according to renal status

From: rs1888747 polymorphism in the FRMD3 gene, gene and protein expression: role in diabetic kidney disease

Renal status

Genotype

Normoalbuminuria (N = 380)

Microalbuminuria (N = 323)

Macro/ESRD (N = 395)

P*

P**

CC

41 (10.8)

25 (7.7)

24 (6.3)

0.04

0.05

GC

152 (40.0)

138 (42.7)

160 (40.9)

  

GG

187 (49.2)

160 (49.5)

211 (52.8)

  

C allele

0.31

0.29

0.26

0.02

0.03

  1. Data expressed as number of cases (%)
  2. * P for comparisons among the three groups (normo- vs. micro- vs. macroalbuminuric/ESRD)
  3. ** P for comparison between normo- and macro/ESRD groups