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Table 1 Genotype distributions in T2DM patients with (cases) or without DKD (controls)

From: rs1888747 polymorphism in the FRMD3 gene, gene and protein expression: role in diabetic kidney disease

Polymorphism Controls (n = 380) Cases (n = 718) P Dominant: OR (95 % CI)/P Recessive: OR (95 % CI)/P Additive: OR (95 % CI)/P
rs1888747
 CC 10.8 (41) 6.8 (49) 0.037 0.91 (0.71–1.16)/0.476 0.60 (0.39–0.94)/0.031 0.60 (0.38–0.95)/0.036
 CG 40.0 (152) 41.5 (298)
 GG 49.2 (187) 51.7 (371)
rs9521445
 AA 18.9 (72) 22.3 (160) 0.146 0.94 (0.71–1.23)/0.688 1.23 (0.90–1.67)/0.226 1.12 (0.78–1.61)/0.598
 AC 53.2 (202) 48.5 (348)
 CC 27.9 (106) 29.2 (210)
rs39075
 AA 17.9 (68) 19.4 (139) 0.139 0.85 (0.66–1.11)/0.264 1.10 (0.80–1.52)/0.611 0.97 (0.68–1.40)/0.963
 AG 49.5 (188) 44.4 (319)
 GG 32.6 (124) 36.2 (260)
rs451041
 AA 23.4 (89) 21.3 (153) 0.318 0.86 (0.65–1.13)/0.305 0.89 (0.66–1.19)/0.467 0.82 (0.58–1.16)/0.296
 AG 48.2 (183) 47.1 (338)
 GG 28.4 (108) 31.6 (227)
rs1041466
 GG 14.2 (54) 17.3 (124) 0.059 0.87 (0.67–1.13)/0.314 1.26 (0.89–1.78)/0.221 1.11 (0.76–1.63)/0.659
 AG 51.1 (194) 44.7 (321)
 AA 34.7 (132) 38.0 (273)
rs1411766
 AA 10.0 (38) 12.6 (91) 0.399 1.25 (0.97–1.60)/0.095 1.31 (0.88–1.95)/0.226 1.41 (0.93–2.13)/0.131
 AG 34.0 (129) 36.8 (264)
 GG 56.0 (213) 50.6 (363)
rs6492208
 CC 20.7 (79) 19.9 (143) 0.461 1.01 (0.78–1.31)/1.000 0.95 (0.70–1.29)/0.792 0.96 (0.68–1.36)/0.898
 CT 43.9 (167) 45.0 (323)
 TT 35.4 (134) 35.1 (252)
  1. Data are presented as % (n)
  2. T2DM type 2 diabetes mellitus, DKD diabetic kidney disease