Elevated glycated hemoglobin levels impair blood pressure in children and adolescents with type 1 diabetes mellitus

Sandra de Oliveira; Dahan da Cunha Nascimento; Ramires Alsamir Tibana; Samuel Lima de Oliveira; Ivo Vieira de Sousa Neto; Roberta Kelly Menezes Maciel Falleiros; Leonardo Garcia Miranda; Hermelinda Cordeiro Pedrosa; James Wilfred Navalta; Guilherme Borges Pereira; Jonato Prestes

doi:10.1186/s13098-015-0118-0

Table 1 Differences between groups and gender demonstrated by means and standard deviation (SD)

From: Elevated glycated hemoglobin levels impair blood pressure in children and adolescents with type 1 diabetes mellitus

	Normotensive	Prehypertension	P	P ^b	Boys	Girls
Disease duration, years	5.32 ± 3.62	7.54 ± 3.78*	0.029	0.758	6.31 ± 4.26	6.00 ± 3.38
Age, years	12.78 ± 1.16	13.27 ± 1.20	0.132	0.132	13.20 ± 1.36	12.74 ± 0.99
Body weight, kg	46.40 ± 9.04	52.38 ± 6.90*	0.013	0.852	48.35 ± 8.09	48.80 ± 9.50
Height, cm	1.56 ± 0.06	1.59 ± 0.07	0.082	0.077	1.59 ± 0.07	1.55 ± 0.06
Body mass index, kg/m²	19.09 ± 3.10	20.58 ± 2.48	0.080	0.172	19.07 ± 2.30	20.20 ± 3.45
Z score body weight^a	−0.57 (−4.72 to 1.62)	0.05 (−1.63 to 1.33)*	0.042	0.731	−0.11 (−4.72 to 1.62)	−0.50 (−2.15 to 1.34)
Z score height^a	−0.73 (−1.89 to 1.68)	−0.21 (−2.21 to 1.18)	0.154	0.747	−0.68 (−1.75 to 1.18)	−0.40 (−2.21 to 1.68)
Z score body mass index^a	−0.03 (−4.72 to 1.58)	0.23 (−0.95 to 1.17)	0.213	0.642	0.04 (−1.69 to 1.41)	0.15 (−4.72 to 1.58)
SBP, mmHg	107.86 ± 7.32	122.59 ± 6.88*	0.001	0.498	112.34 ± 11.83	114.12 ± 8.22
DBP, mmHg	66.39 ± 5.49	77.04 ± 10.59*	0.001	0.272	68.93 ± 9.83	71.58 ± 8.64
HR, bpm	86.83 ± 15.001	92.27 ± 18.12	0.221	0.024*	83.92 ± 15.22	95.53 ± 16.17
Glycaemia, mg/dl	215.47 ± 90.91	204.00 ± 113.03	0.752	0.978	212.15 ± 82.62	211.21 ± 117.94
HbA₁, %	9.74 ± 1.98	11.58 ± 3.08*	0.037	0.573	10.17 ± 2.46	10.60 ± 2.67
HDL, mg/dl	54.47 ± 8.45	51.14 ± 12.22	0.333	0.782	52.80 ± 8.48	53.75 ± 12.00
LDL, mg/dl	102.22 ± 25.78	102.50 ± 38.72	0.979	0.814	103.39 ± 30.86	100.93 ± 31.63
Triglycerides, mg/dl	89.44 ± 40.29	92.53 ± 44.39	0.820	0.138	81.91 ± 38.10	101.00 ± 43.57
Total cholesterol, mg/dl	169.78 ± 39.06	177.00 ± 38.67	0.566	0.750	170.52 ± 44.92	174.35 ± 30.87

SBP systolic blood pressure, DBP diastolic blood pressure, HR heart rate, HbA ₁ glycated hemoglobin
* P ≤ 0.05
^aData not normally distributed is presented as median, minimum and maximum values
^b Comparisons between sexes

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