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Table 1 Shows sample sizes, distributions of age, gender, comorbidities, HbA1c/hyperglycemia, BMI, hepatic profile, lipid profile, and medication use of the patient and control groups

From: Study on inflammation-related genes and microRNAs, with special emphasis on the vascular repair factor HGF and miR-574-3p, in monocytes and serum of patients with T2D

  HC T2D HC vs. T2D
p value
Group size n 44 64  
Age mean (range) 53 (32–87) 61 (37–85) 0.00**
BMI mean (range) % 28.7 (23–42) 29.5 (22–49) 0.471
 Normal 18.2 % 16.1 %
 Overweight 45.5 % 40.3 %
 Obese 36.4 % 43.5 %
Gender
 Female n (%) 31 (70.5 %) 40 (62.5 %) NA
 Male n (%) 13 (29.5 %) 24 (37.5 %) NA
Glucose state
 Fasting glucose mg/dL, mean (range) % 88 (60.9–180.5) 146 (59–397) 0.00**
  Normal 88.6 % 45.3 %
  High 11.4 % 54.7 %
 HbA1C, mean (range) % 5.6 (3.9–6.9) 7.0 (3.2–12.5) 0.00**
  Normal 81.8 % 35.7 %
  High 18.25 % 62.5 %
Lipid profile
 Total cholesterol mg/dL, mean (range) % 237 (131–328) 237 (143–465) 0.99
  Normal 31.8 % 37.5 %
  High 68.2 % 62.5 %
 TG mean mg/dL, mean (range) % 194 (85–547) 205 (76–628) 0.56
  Normal 63.6 % 60.9 %
  High 36.4 % 39.1 %
 HDL mean mg/dL, mean (range) % 43 (27–87) 43 (17–85) 0.81
  Normal 54.5 % 57.8 %
  High 45.5 % 42.2 %
 LDL mg/dL, mean (range) % 158 (78–266) 158 (77–395) 0.95
  Normal 50 % 56.3 %
  High 50 % 43.8 %
Hepatic profile
 ASAT mean mg/dL, mean (range) % 41.3 (19–95) 33.3 (6.0–78) 0.01*
  Normal 48.7 % 70.8 %
  High 51.3 % 29.2 %
 ALAT mean mg/dL, mean (range) % 44.7 (10–135) 38.8 (7.0–131) 0.252
  Normal 47.4 % 64.6 %
  High 52.6 % 35.4 %
Medication
 Metformin 0 % 44.6 %  
 Insulin 0 % 9.2 %  
 Both medications 0 % 15.4 %  
 Any anti-diabetic medication 100 % 30.8 %  
 Statins (%) 0 % 0 %  
  1. Level of total cholesterol (TC) more than 200 mg/dL, triglycerides (TG) more than 200 mg/dL, high-density cholesterol fraction (HDL) <45 mg/dL in women, <40 mg/dL in men and low-density cholesterol fraction (LDL) more than 130 mg/dL was used for the identification of abnormal values
  2. Values in italics denote a significant difference between two groups
  3. * p 0.01; ** p 0.001