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Table 2 Risk ratios (RR) and their 95 % confidence intervals (CI) from Cox model for association of fibrinogen on MetS in male and female

From: A new insight into the role of plasma fibrinogen in the development of metabolic syndrome from a prospective cohort study in urban Han Chinese population

 

Total (n = 6209)

Male (n = 3637)

Female (n = 2260)

Model 1

Model 2

Model 1

Model 2

Model 1

Model 2

Model 3

Fibrinogen quartiles

 Q2 vs. Q1

1.12 (0.94,1.33)

1.03 (0.87,1.23)

1.09 (0.89,1.32)

1.00 (0.82,1.22)

1.43 (0.97,2.12)

1.33 (0.90,1.96)

1.04 (0.58,1.87)

 Q3 vs. Q1

1.19 (1.01,1.41)

1.01 (0.85,1.20)

1.11 (0.91,1.35)

0.92 (0.76,1.12)

1.66 (1.14,2.4)

1.45 (1.00,2.10)

1.22 (0.71,2.10)

 Q4 vs. Q1

1.39 (1.17,1.65)

1.15 (0.97,1.36)

1.22 (1,1.48)

1.05 (0.86,1.28)

1.84 (1.27,2.66)

1.48 (1.02,2.13)

1.03 (0.60,1.77)

P value for trend

0.0019

0.1925

0.0523

0.8046

0.0011

0.0498

 

Age

1.03 (1.02,1.03)

1.02 (1.01,1.02)

1.02 (1.01,1.02)

1.01 (1.00,1.02)

1.05 (1.04,1.06)

1.03 (1.02,1.04)

1.03 (1.02,1.04)

Female

0.65 (0.57,0.75)

0.89 (0.77,1.03)

     

Former smoking

1.06 (0.79,1.42)

1.22 (0.91,1.64)

1.18 (0.87,1.59)

1.32 (0.98,1.79)

0.39 (0.09,1.61)

0.45 (0.11,1.88)

0.46 (0.11,1.94)

Current smoking

0.95 (0.83,1.09)

0.99 (0.86,1.14)

0.93 (0.81,1.08)

0.98 (0.85,1.14)

0.87 (0.49,1.52)

0.96 (0.55,1.67)

0.96 (0.55,1.68)

Frequent drinker

1.34 (1.17,1.55)

1.19 (1.03,1.37)

1.3 (1.12,1.51)

1.18 (1.02,1.37)

0.99 (0.57,1.72)

0.96 (0.55,1.67)

0.95 (0.54,1.65)

Vegetarian

0.77 (0.68,0.89)

0.83 (0.72,0.95)

0.78 (0.65,0.92)

0.83 (0.70,0.99)

0.77 (0.61,0.97)

0.81 (0.64,1.02)

0.81 (0.64,1.02)

Regular exerciser

1.03 (0.92,1.16)

1.02 (0.91,1.15)

1.02 (0.89,1.17)

1.02 (0.89,1.17)

1.17 (0.93,1.46)

1.06 (0.84,1.32)

1.04 (0.83,1.31)

Overweight

 

3.60 (3.15,4.11)

 

3.29 (2.81,3.87)

 

4.11 (3.23,5.22)

2.76 (1.5,5.06)

Dyslipidemia

 

2.36 (2.06,2.71)

 

2.13 (1.81,2.50)

 

2.75 (2.11,3.57)

2.82 (2.16,3.67)

Hypertension

 

3.04 (2.64,3.5)

 

2.83 (2.39,3.35)

 

3.20 (2.46,4.18)

3.26 (2.49,4.25)

Hyperglycemia

3.48 (2.87,4.23)

 

3.26 (2.59,4.11)

 

3.85 (2.70,5.48)

3.95 (2.76,5.63)

Overweight*fibrinogen

 1*Q2

      

1.54 (0.70,3.38)

 1*Q3

      

1.37 (0.66,2.88)

 1*Q4

      

1.85 (0.90,3.80)

  1. For fibrinogen quartiles, in whole participates, Q1 was defined as fibrinogen ≤2.79 g/l, Q2 was defined as fibrinogen in 2.79–3.20 g/l, Q3 was defined as fibrinogen in 3.20–3.567 g/l, and Q4 was defined as fibrinogen >3.67 g/l; in male, Q1 was defined as fibrinogen ≤2.71 g/l, Q2 was defined as fibrinogen in 2.71–3.14 g/l, Q3 was defined as fibrinogen in 3.14–3.58 g/l, and Q4 was defined as fibrinogen >3.58 g/l; in female, Q1 was defined as fibrinogen ≤2.92 g/l, Q2 was defined as fibrinogen in 2.92–3.32 g/l, Q3 was defined as fibrinogen in 3.32–3.81 g/l, and Q4 was defined as fibrinogen >3.81 g/l
  2. Model 1. adjusted by baseline covariates of age, gender, smoking, alcohol, vegetarian diet, exercise
  3. Model 2. adjusted by baseline covariates of age, gender, smoking, alcohol, vegetarian diet, exercise, overweight, hypertension, hyperglycemia, dyslipidemia
  4. Model 3. adjusted by baseline covariates of age, gender, smoking, alcohol, vegetarian diet, exercise, overweight, hypertension, hyperglycemia, dyslipidemia, interaction of fibrinogen and overweight