Table 1 Quantitative analyses of transendothelial transfer of dextran and THP-1 cells and MLC phosphorylation

Control

5

9.09 ± 0.49

7.00 ± 1.22

0.00 ± 0.00

High glucose

5

16.72 ± 1.51^*

30.00 ± 6.44^*

0.73 ± 0.28^*

dnRhoA

5

10.31 ± 1.97

10.00 ± 1.87

0.16 ± 0.02

Y27632

5

9.98 ± 0.78

9.00 ± 1.58

0.23 ± 0.03

High-glucose + dnRhoA

5

13.04 ± 0.91^#

17.00 ± 1.87^*,#

0.34 ± 0.04^#

High glucose + Y27632

5

10.96 ± 0.39^#

18.20 ± 1.79^*,#

0.46 ± 0.03^#

F

29.503

39.210

24.205

P

0.000

0.000

0.000