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Table 1 Quantitative analyses of transendothelial transfer of dextran and THP-1 cells and MLC phosphorylation

From: Effects of high glucose on human umbilical vein endothelial cell permeability and myosin light chain phosphorylation

Group n Transendothelial transfer rate of dextran (%dextran/h/cm2) THP-1 transendothelial migration (cell/HP) MLC phosphorylation
Control 5 9.09 ± 0.49 7.00 ± 1.22 0.00 ± 0.00
High glucose 5 16.72 ± 1.51* 30.00 ± 6.44* 0.73 ± 0.28*
dnRhoA 5 10.31 ± 1.97 10.00 ± 1.87 0.16 ± 0.02
Y27632 5 9.98 ± 0.78 9.00 ± 1.58 0.23 ± 0.03
High-glucose + dnRhoA 5 13.04 ± 0.91# 17.00 ± 1.87*,# 0.34 ± 0.04#
High glucose + Y27632 5 10.96 ± 0.39# 18.20 ± 1.79*,# 0.46 ± 0.03#
F   29.503 39.210 24.205
P   0.000 0.000 0.000
  1. * P < 0.01 vs. control group; # P < 0.01 vs. high-glucose group