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Fig. 2 | Diabetology & Metabolic Syndrome

Fig. 2

From: Effects of high glucose on human umbilical vein endothelial cell permeability and myosin light chain phosphorylation

Fig. 2

Effects of dnRhoA and Y27632 on high-glucose-induced MLC phosphorylation. MLC phosphorylation was not detectable in HUVECs cultured at normal glucose concentration but was significantly increased after stimulation with high glucose. MLC phosphorylation was significantly reduced by blocking RhoA and ROCK activities with dnRhoA and Y27632, respectively. Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) was used as an internal reference. a Western blot assay; b bar graph. *P < 0.01 vs. control group; # P < 0.01 vs. high-glucose group

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