Fig. 5
From: Progesterone ameliorates diabetic nephropathy in streptozotocin-induced diabetic Rats
Immunohistochemistry and real-time PCR detect that progesterone replacement partially restores the nephrin expression in the diabetic kidney. A immunohistochemical stain of the kidney sections (hematoxylin staining; magnification, ×400) show that the nephrin immunostaining (brown staining) in the glomeruli was much stronger in the ND group compared with the D and the D-OVX groups (arrows). Progesterone replacement inhibited the decrease in the nephrin immunostaining in the D + OVX + P group. B nephrin mRNA expressions by real-time PCR. Data represent the mean ± SEM. Means with different superscript letters are significantly different from one another (P < 0.05)