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Fig. 5 | Diabetology & Metabolic Syndrome

Fig. 5

From: Progesterone ameliorates diabetic nephropathy in streptozotocin-induced diabetic Rats

Fig. 5

Immunohistochemistry and real-time PCR detect that progesterone replacement partially restores the nephrin expression in the diabetic kidney. A immunohistochemical stain of the kidney sections (hematoxylin staining; magnification, ×400) show that the nephrin immunostaining (brown staining) in the glomeruli was much stronger in the ND group compared with the D and the D-OVX groups (arrows). Progesterone replacement inhibited the decrease in the nephrin immunostaining in the D + OVX + P group. B nephrin mRNA expressions by real-time PCR. Data represent the mean ± SEM. Means with different superscript letters are significantly different from one another (P < 0.05)

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