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Fig. 4 | Diabetology & Metabolic Syndrome

Fig. 4

From: DPP-4 inhibitor sitagliptin prevents inflammation and oxidative stress of heart and kidney in two kidney and one clip (2K1C) rats

Fig. 4

Effect of sitagliptin on kidney fibrosis in 2K1C model rats. a Sham; b Sham + Sitagliptin; c 2K1C and d 2K1C + Sitagliptin. No pathological collagen tissue deposition was observed in Sham animals (a) and Sham + Sitagliptin (b). Observe the greater collagen deposition in the left kidney of 2K1C rats (c arrows). No/less collagen tissue deposition can be observed in right kidney of all 2K1C animals treated with sitagliptin (d). Magnification ×40. fb fibrosis

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