Skip to main content


Fig. 3 | Diabetology & Metabolic Syndrome

Fig. 3

From: DPP-4 inhibitor sitagliptin prevents inflammation and oxidative stress of heart and kidney in two kidney and one clip (2K1C) rats

Fig. 3

Effect of sitagliptin on cardiac fibrosis in 2K1C model rats. Picrosirius red staining for fibrosis. a Sham; b Sham + Sitagliptin; c 2K1C and d 2K1C + Sitagliptin. No pathological collagen tissue deposition was observed in Sham animals (a) and Sham + Sitagliptin (b). Observe the greater collagen deposition in the left ventricle of heart of 2K1C rats (c arrows). No/less collagen tissue deposition can be observed in left ventricle of heart of all 2K1C animals treated with sitagliptin (d). Magnification ×40. fb fibrosis

Back to article page