Fig. 3From: DPP-4 inhibitor sitagliptin prevents inflammation and oxidative stress of heart and kidney in two kidney and one clip (2K1C) ratsEffect of sitagliptin on cardiac fibrosis in 2K1C model rats. Picrosirius red staining for fibrosis. a Sham; b Sham + Sitagliptin; c 2K1C and d 2K1C + Sitagliptin. No pathological collagen tissue deposition was observed in Sham animals (a) and Sham + Sitagliptin (b). Observe the greater collagen deposition in the left ventricle of heart of 2K1C rats (c arrows). No/less collagen tissue deposition can be observed in left ventricle of heart of all 2K1C animals treated with sitagliptin (d). Magnification ×40. fb fibrosisBack to article page