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Table 1 Clinical and laboratory profile of patients with type 2 diabetes mellitus according to renal status

From: Endothelin-1 gene polymorphisms and diabetic kidney disease in patients with type 2 diabetes mellitus

  Controls (n = 308) Cases (n = 240) P*
Male gender, n (%) 118 (38.3) 144 (60.0) <0.001
Duration of diabetes (years) 13.4 ± 7.2 17.2 ± 9.6 <0.001
Age (years) 60.6 ± 9.7 61.2 ± 9.9 0.477
BMI (kg/m2) 28.4 ± 4.7 28.4 ± 5.2 0.999
Systolic blood pressure (mmHg) 142 ± 23.5 149 ± 24.1 <0.001
Diastolic blood pressure (mmHg) 85 ± 13.5 86 ± 14.0 0.398
HbA1c (%) 6.88 ± 1.57 6.85 ± 2.06 0.847
Fasting plasma glucose (mg/dL) 161.8 ± 59.5 168.3 ± 75.3 0.260
Serum creatinine (mg/dL) 0.9 (0.5–1.4) 2.9 (0.6–13.9) <0.001
Cholesterol, total (mg/dL) 206 ± 44.2 203.1 ± 52.6 0.469
Cholesterol, HDL (mg/dL) 46.7 ± 11.5 41.7 ± 11.7 <0.001
Triglycerides (mg/dL) 143 (40–659) 171 (45–1265) <0.001
  1. Data expressed as mean ± SD, median (range) or %
  2. * P values computed by Chi square or Student’s t test as appropriate. Bonferroni threshold for multiple comparisons = 0.0042