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Table 3 The genotype distribution of rs864745 (JAZF1) and rs796158 (TSPAN8/LGR5) polymorphisms in T2DM and control group stratified based gender

From: Association of JAZF1 and TSPAN8/LGR5 variants in relation to type 2 diabetes mellitus in a Saudi population

 

Males

Females

Odds Ratio (95 % CI)a

p value

Odds ratio (95 % CI)b

p value

Odds Ratio (95 % CI)a

p value

Odds ratio (95 % CI)a

p value

JAZF1 (rs864745)

 AA

Reference

   

Reference

   

 AG

2.0 (1.1, 3.9)

0.02

2.0 (1.0, 4.0)

0.04

1.8 (1.0, 3.1)

0.04

2.2 (1.1, 4.3)

0.01

 GG

1.8 (0.96, 3.5)

0.06

1.7 (0.87, 3.5)

0.11

1.7 (0.98, 3.0)

0.05

2.2 (1.2, 4.2)

0.01

 AG + GG

1.9 (1.1, 3.6)

0.03

1.9 (0.99, 3.6)

0.05

1.7 (1.0, 2.9)

0.03

2.2 (1.2, 4.1)

0.008

TSPAN8 (rs7961581)

 CC

0.64 (0.33, 1.2)

0.19

0.72 (0.36, 1.4)

0.35

1.1 (0.66, 1.9)

0.62

1.4 (0.76, 2.5)

0.27

 TC

0.74 (0.47, 1.2)

0.21

0.69 (0.42, 1.1)

0.14

1.6 (1.1, 2.4)

0.02

1.8 (1.1, 2.9)

0.01

 TT

Reference

 

Reference

 

Reference

 

Reference

 

 CC + TC

0.72 (0.47, 1.1)

0.12

0.70 (0.45, 1.1)

0.12

1.5 (1.0, 2.1)

0.04

1.7 (1.1, 2.6)

0.01

  1. aCrude odds ratio (95 % CI);
  2. bOdds ratio (95 % CI) controlled for age and BMI
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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