Table 1 Characteristics of studied groups
From: Homocysteine levels in women with a history of gestational diabetes mellitus
Parameter | C (mean ± SD, n = 50) | pGDM (mean ± SD, n = 199) | p |
|---|---|---|---|
Age (years) | 36.8 ± 5.6 | 38.4 ± 6.6 | NS |
Number of pregnancies | 1.9 ± 2.1 | 2.4 ± 1.4 | NS |
Number of deliveries | 1.8 ± 2.4 | 2.1 ± 1.2 | NS |
Time since pGDM/pregnancy (years) | 7.8±1.0 | 7.4 ± 0.7 | NS |
Body weight before pregnancy (kg) | 61.6 ± 11.1 | 63.3 ± 13.1 | NS |
Body weight (kg) | 68.7 ± 14.9 | 67.9 ± 15.2 | NS |
BMI before pregnancy (kg/m2) | 21.9 ± 3.9 | 22.5 ± 4.1 | NS |
BMI (kg/m2) | 25.4 ± 5.0 | 25.5 ± 5.6 | NS |
WHR | 0.84 ± 0.07 | 0.86 ± 0.09 | NS |
Adipose tissue mass (kg) | 22.6 ± 11.1 | 21.9 ± 10.2 | NS |
Lean body mass (kg) | 46.1 ± 4.8 | 45.5 ± 6.1 | NS |
HbA1c (%) | 5.4 ± 0.4 | 5.6 ± 0.4 | <0.01 |
Glucose 0’ (mmol/L) | 4.9 ± 0.6 | 5.3 ± 0.7 | <0.0001 |
Glucose 60’ (mmol/L) | 5.8 ± 1.9 | 8.3 ± 2.6 | <0.0001 |
Glucose 120’ (mmol/L) | 4.8 ± 1.1 | 6.4 ± 2.2 | <0.0001 |
Insulin 0’ (µIU/mL) | 13.7 ± 8.5 | 13.7 ± 8.7 | NS |
Insulin 60’ (µIU/mL) | 83.8 ± 41.1 | 106.8 ± 62.6 | <0.03 |
Insulin 120’ (µIU/mL) | 47.5 ± 30.6 | 74.6 ± 58.7 | <0.002 |
HOMA-IR | 1.73 ± 1.03 | 1.76 ± 1.05 | NS |
Homocysteine (µmol/L) | 7.56 ± 3.55 | 7.63 ± 2.66 | NS |
Total cholesterol (mmol/L) | 4.99 ± 0.88 | 4.93 ± 1.0 | NS |
HDL-cholesterol (mmol/L) | 1.71 ± 0.47 | 1.78 ± 0.47 | NS |
LDL-cholesterol (mmol/L) | 2.79 ± 0.8 | 2.68 ± 0.93 | NS |
Triglycerides (mmol/L) | 1.06 ± 0.97 | 1.11 ± 0.69 | NS |
Creatinine (µmol/L) | 56.6 ± 9.7 | 58.3 ± 9.7 | NS |
Creatinine clearance (mL/min) | 132.5 ± 33.2 | 126.3 ± 32.0 | NS |