Skip to main content

Advertisement

Table 2 Circulating adipokine levels and insulin-resistance index in subjects with and without cardiac or metabolic syndrome X

From: Circulating adipokines and insulin resistance in subjects with combined cardiac and metabolic syndrome X

  CSX (−) MetX (−) (N = 39) CSX (+) MetX (−) (N = 35) CSX (−) MetX (+) (N = 15) CSX (+) MetX (+) (N = 24) p a p b
Adiponectin (μg/mL) 12.3 (7.0, 18.9) 3.4 (2.3, 7.2) 4.0 (2.0, 9.1) 2.8 (1.7, 7.7) <0.001 <0.001
Leptin (ng/mL) 3.3 (1.3, 8.1) 5.1 (3.1, 11.0) 8.1 (5.1, 18.5) 8.7 (6.3, 17.4) <0.001 <0.001
HOMA-IR 1.04 (0.72, 2.47) 1.93 (1.28, 2.62) 2.40 (1.78, 4.21) 2.23 (1.48, 5.89) 0.009 0.005
  1. Data are expressed as median (interquartile range, 25th percentile to 75th percentile) because of a non-normal distribution
  2. CSX cardiac syndrome X, MetX metabolic syndrome X, HOMA-IR homeostasis model assessment (HOMA) index of insulin resistance = (fasting glucose mg/dL × fasting insulin μU/mL)/405
  3. Mann–Whitney U test for comparisons below (Bonferroni corrected p cut-off value for significance <0.0083)
  4. Adiponectin
  5. Adiponectin CSX(−) MetX (−) vs. CSX (+) MetX (+), p < 0.001
  6. Adiponectin CSX(−) MetX (−) vs. CSX (+) MetX (−), p < 0.001
  7. Adiponectin CSX (−) MetX (−) vs. CSX (−) MetX (+), p = 0.002
  8. Adiponectin CSX (+) MetX (−) vs. CSX (+) MetX (+), p = 0.260
  9. Adiponectin CSX (−) MetX (+) vs. CSX (+) MetX (+), p = 0.326
  10. Adiponectin CSX (−) MetX (+) vs. CSX (+) MetX (−), p = 0.924
  11. Leptin
  12. Leptin CSX(−) MetX (−) vs. CSX (+) MetX (+), p < 0.001
  13. Leptin CSX(−) MetX (−) vs. CSX (+) MetX (−), p = 0.067
  14. Leptin CSX (−) MetX (−) vs. CSX (−) MetX (+), p = 0.002
  15. Leptin CSX (+) MetX (−) vs. CSX (+) MetX (+), p = 0.030
  16. Leptin CSX (−) MetX (+) vs. CSX (+) MetX (+), p = 0.603
  17. Leptin CSX (−) MetX (+) vs. CSX (+) MetX (−), p = 0.105
  18. HOMA-IR
  19. HOMA-IR CSX(−) MetX (−) vs. CSX (+) MetX (+), p = 0.005
  20. HOMA-IR CSX(−) MetX (−) vs. CSX (+) MetX (−), p = 0.023
  21. HOMA-IR CSX (−) MetX (−) vs. CSX (−) MetX (+), p = 0.044
  22. HOMA-IR CSX (+) MetX (−) vs. CSX (+) MetX (+), p = 0.151
  23. HOMA-IR CSX (−) MetX (+) vs. CSX (+) MetX (+), p = 0.862
  24. HOMA-IR CSX (−) MetX (+) vs. CSX (+) MetX (−), p = 0.130
  25. ap value for Kruskal–Wallis test among the four groups
  26. bp value Mann–Whitney U test for CSX (+) and MetX (+) vs. CSX (−) and MetX (−)