|
CSX (−)
MetX (−)
(N = 39)
|
CSX (+)
MetX (−)
(N = 35)
|
CSX (−)
MetX (+)
(N = 15)
|
CSX (+)
MetX (+)
(N = 24)
|
p
a
|
p
b
|
---|
Gender (M/F)
|
25/14
|
25/10
|
8/7
|
14/10
|
0.593
| |
Age (years)
|
59 (49, 68)
|
56 (50, 65)
|
54 (46, 61)
|
55 (50, 66)
|
0.638
|
0.655
|
Hypertension (N) (%)
|
8 (20.5 %)
|
15 (42.9 %)
|
9 (60 %)
|
22 (91.7 %)
|
<0.001
| |
Body mass index (kg/m2)
|
23.8 (22.4, 26.0)
|
25.2 (23.9, 27.6)
|
28.6 (25.5, 31.5)
|
27.7 (24.6, 30.8)
|
<0.001
|
<0.001
|
Current smoking (N) (%)
|
2 (5.1 %)
|
6 (17.1 %)
|
4 (26.7 %)
|
9 (37.5 %)
|
0.012
| |
Total cholesterol (mg/dL)
|
151 (134, 170)
|
164 (146, 193)
|
166 (135, 196)
|
185 (159, 211)
|
0.004
|
<0.001
|
Calculated LDL-C (mg/dL)
|
83 (74, 104)
|
96 (83, 120)
|
93 (67, 106)
|
97 (76, 134)
|
0.105
|
0.057
|
HDL-C (mg/dL)
|
48 (41, 60)
|
51 (46, 56)
|
42 (36, 44)
|
43 (38, 48)
|
<0.001
|
0.015
|
Triglycerides (mg/dL)
|
86 (51, 115)
|
83 (64, 113)
|
156 (116, 192)
|
203 (145, 240)
|
<0.001
|
<0.001
|
Fasting plasma glucose (mg/dL)
|
94 (88, 112)
|
95 (89, 113)
|
110 (102, 126)
|
106 (93, 128)
|
0.012
|
0.015
|
Fasting serum insulin (µIU/mL)
|
4.5 (2.9, 9.9)
|
8.4 (4.9, 10.6)
|
9.2 (5.9, 16.7)
|
9.4 (5.1, 19.9)
|
0.022
|
0.012
|
Hs-CRP (mg/dL)
|
0.127 (0.057, 0.344)
|
0.079 (0.036, 0.297)
|
0.220 (0.152, 0.530)
|
0.138 (0.082, 0.318)
|
0.180
|
0.661
|
Medication use
|
Use of statin (N) (%)
|
3 (7.7 %)
|
2 (5.7 %)
|
0
|
3 (12.5 %)
|
0.506
| |
Use of ACEI or ARB (N) (%)
|
12 (30.8 %)
|
7 (20 %)
|
3 (20 %)
|
10 (41.7 %)
|
0.270
| |
- Data are expressed as median (interquartile range, 25th percentile to 75th percentile) because of a non-normal distribution
-
ACEI angiotensin converting enzyme inhibitors, ARB angiotensin receptor blockers, CSX cardiac syndrome X, HDL-C high-density lipoprotein cholesterol, Hs-CRP high sensitivity C-reactive protein, LDL-C low-density lipoprotein cholesterol, MetX metabolic syndrome X, Statin HMG-CoA reductase inhibitors
-
ap value for Kruskal–Wallis test among the four groups
-
bp value Mann–Whitney U test for CSX (+) and MetX (+) vs. CSX (−) and MetX (−)
- Mann–Whitney U test, Bonferroni corrected p cut-off value for significance <0.0083