Skip to main content

Table 2 Comparisons of glucose and insulin concentrations during OGTT in pGDM and control groups

From: Glycemic variability in normal glucose tolerance women with the previous gestational diabetes mellitus

Variables

pGDM group

Control group

t

p

n

48

48

–

–

Glu0 (mmol/L)

5.5 ± 0.6

5.1 ± 0.5

3.845

0.000

Glu30 (mmol/L)

9.0 ± 1.7

7.5 ± 1.4

4.771

0.000

Glu60 (mmol/L)

8.8 ± 2.8

6.7 ± 2.3

4.071

0.000

Glu120 (mmol/L)

6.0 ± 1.1

5.4 ± 1.4

2.722

0.008

Glu180 (mmol/L)

4.9 ± 1.0

4.8 ± 1.0

0.677

0.500

Ins0 (miu/L)

6.3 (3.9–9.7)

5.6 (4.0–7.8)

–

0.391*

Ins30 (miu/L)

54.6 (36.4–88.7)

56.1 (37.9–77.0)

–

0.800*

Ins60 (miu/L)

63.1 (40.9–85.0)

44.1 (28.5–65.4)

–

0.011*

Ins120 (miu/L)

31.3 (14.9–42.6)

28.5 (21.6–40.1)

–

0.823*

Ins180 (miu/L)

9.2 (5.5–13.6)

8.1 (4.7–17.2)

–

0.496*

AUCglu (mmol/L·h)

18.4 ± 2.8

15.7 ± 2.5

4.712

0.000

AUCins (miu/L·h)

114.7 (74.17–163.8)

99.6 (75.2–132.1)

–

0.356*

AUCins/glu

5.6 (4.0–7.8)

6.6 (5.6–7.7)

–

0.031*

ISI

140.7 (81.9–190.0)

155.0 (120.3–205.7)

–

0.034*

ISSI-2

729.8 (496.9–943.0)

1027.2 (872.7–1177.5)

–

0.000*

  1. Non-normally distributed values are given as the median (25 and 75 % interquartiles)
  2. pGDM group: NGT women with the previous GDM; Control group: NGT women without the previous GDM
  3. Glut plasma glucose concentrations at time t during OGTT, Inst plasma insulin concentrations at time t during OGTT, AUC glu the area under the curve of glucose in 180 min, AUC ins the area under the curve of insulin in 180 min, ISI insulin sensitivity index, AUC ins/glu insulin secretion index, ISSI-2 insulin secretion-sensitivity index-2
  4. * Test with Mann–Whitney U test