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Table 4 Anthropometric, biochemical and endothelial indices according to metabolic status at follow up

From: The impact of long-term changes in metabolic status on cardiovascular biomarkers and microvascular endothelial function in middle-aged men: a 25-year prospective study

 

Metabolic status at follow-up

Metabolically healthy (0–1 factors) n = 47

Metabolically unhealthy (≥2 factors) n = 54

Age, years

61.0 ± 10.1

59.1 ± 8.4

Body fat,  %

17.1 ± 4.0

22.2 ± 4.7***

Waist circumference ≥102 cm, n

1

23***

BMI ≥30 kg/m2, n

0

8*

RHI

2.06 ± 0.48

1.91 ± 0.42*

RHI <1.67, n

5

15*

Uric acid, µmol/L

0.08 ± 0.01

0.10 ± 0.02*

hsCRP, mg/L

2.31 ± 1.15

2.73 ± 1.14*

Homocysteine, µmol/lL

13.25 ± 6.3

14.95 ± 4.7

ox-LDL (median), ng/mL

99.85 ± 181.4 (29.1)

115.92 ± 226.7 (39.5)

sICAM-1, ng/mL

486.60 ± 117

502.25 ± 143.53

sVCAM-1, ng/mL

657.58 ± 250.0

749.05 ± 263.4

Interleukin-6, pg/mL

2.67 ± 2.1

2.78 ± 2,7

Leptin, ng/mL

5.91 ± 4.5

7.75 ± 6.4#

Resistin, ng/mL

4.52 ± 1.8

4.99 ± 2.9

Adiponectin, µmol/L

8.15 ± 3.2

7.48 ± 2.5

Adiponectin/leptin ratio

1.41 ± 0.7

0.91 ± 0.4*

Irisin, µmol/L

0.49 ± 0.2

0.50 ± 0.1

EE at baseline, kcal/week

4558.7 ± 3233.0

2638.5 ± 2198.7***

EE at follow-up, kcal/week

3230.8 ± 2150.0

2661.0 ± 2375.6*

VO2max, ml/kg/min

35.1 ± 8.9

30.1 ± 8.2*

PWC, W/kg

2.09

1.83*

Smoking at baseline, n

9

8

Smoking at follow-up, n

3

2

  1. Abbreviations as in the previous tables
  2. * p < 0.05; ** p < 0.01; *** p < 0.001; #p = 0.0502