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Table 4 Anthropometric, biochemical and endothelial indices according to metabolic status at follow up

From: The impact of long-term changes in metabolic status on cardiovascular biomarkers and microvascular endothelial function in middle-aged men: a 25-year prospective study

  Metabolic status at follow-up
Metabolically healthy (0–1 factors) n = 47 Metabolically unhealthy (≥2 factors) n = 54
Age, years 61.0 ± 10.1 59.1 ± 8.4
Body fat,  % 17.1 ± 4.0 22.2 ± 4.7***
Waist circumference ≥102 cm, n 1 23***
BMI ≥30 kg/m2, n 0 8*
RHI 2.06 ± 0.48 1.91 ± 0.42*
RHI <1.67, n 5 15*
Uric acid, µmol/L 0.08 ± 0.01 0.10 ± 0.02*
hsCRP, mg/L 2.31 ± 1.15 2.73 ± 1.14*
Homocysteine, µmol/lL 13.25 ± 6.3 14.95 ± 4.7
ox-LDL (median), ng/mL 99.85 ± 181.4 (29.1) 115.92 ± 226.7 (39.5)
sICAM-1, ng/mL 486.60 ± 117 502.25 ± 143.53
sVCAM-1, ng/mL 657.58 ± 250.0 749.05 ± 263.4
Interleukin-6, pg/mL 2.67 ± 2.1 2.78 ± 2,7
Leptin, ng/mL 5.91 ± 4.5 7.75 ± 6.4#
Resistin, ng/mL 4.52 ± 1.8 4.99 ± 2.9
Adiponectin, µmol/L 8.15 ± 3.2 7.48 ± 2.5
Adiponectin/leptin ratio 1.41 ± 0.7 0.91 ± 0.4*
Irisin, µmol/L 0.49 ± 0.2 0.50 ± 0.1
EE at baseline, kcal/week 4558.7 ± 3233.0 2638.5 ± 2198.7***
EE at follow-up, kcal/week 3230.8 ± 2150.0 2661.0 ± 2375.6*
VO2max, ml/kg/min 35.1 ± 8.9 30.1 ± 8.2*
PWC, W/kg 2.09 1.83*
Smoking at baseline, n 9 8
Smoking at follow-up, n 3 2
  1. Abbreviations as in the previous tables
  2. * p < 0.05; ** p < 0.01; *** p < 0.001; #p = 0.0502