Table 2 Change in levels of clinical variables among 127,977 diabetic subjects between 2009 and 2013

25.6 ± 3.9

25.3 ± 3.9

−0.3 ± 1.8 (n = 71,224)

<0.001*

0.9 ± 0.2

0.9 ± 0.1

0.01 ± 0.2 (n = 47,714)

<0.001*

7.2 ± 1.2

7.0 ± 1.1

−0.2 ± 1.3 (n = 113,066)

<0.001*

136.9 ± 16.9

131.3 ± 15.0

−5.6 ± 19.8 (n = 126,863)

<0.001*

75.4 ± 10.2

72.1 ± 10.0

−3.3 ± 11.0 (n = 126,863)

<0.001*

3.1 ± 0.8

2.4 ± 0.7

−0.7 ± 0.9 (n = 72,040)

<0.001*

1.7 ± 1.1

1.4 ± 0.8

−0.3 ± 1.0 (n = 73,631)

<0.001*

5.1 ± 0.9

4.3 ± 0.8

−0.7 ± 1.0 (n = 74,574)

<0.001*

1.2 ± 0.3

1.3 ± 0.4

0.1 ± 0.3 (n = 73,406)

<0.001*

4.4 ± 1.3

3.5 ± 1.0

−0.9 ± 1.2 (n = 73,294)

<0.001*

4.7 ± 18.6

7.9 ± 35.1

3.2 ± 33.1 (n = 28,250)

<0.001*