Table 2 Initial biochemical parameters of the patients in the intention-to-treat population
|  | Placebo (n = 87) | Pentoxifylline (n = 87) | P-value |
|---|---|---|---|
Serum Cr (mg/dL) | 0.9 ± 0.3 | 0.9 ± 0.2 | 0.165 |
Urinary Cr (mg/dL) | 103 (72-136) | 86 (61-122) | 0.176 |
eGFR (ml/min per 1.73 m2) | 85.4 ± 27.0 | 88.8 ± 24.8 | 0.401 |
Proteinuria (mg/g) | 395 (229–714) | 371 (218–610) | 0.689 |
Albuminuria (mg/g) | 203 (88-513) | 143 (71-315) | 0.201 |
Fasting plasma glucose (mg/dL) | 140 ± 35 | 138 ± 35 | 0.795 |
HbA1c (%) | 7.2 ± 0.8 | 7.5 ± 0.9 | 0.043 |
AST(U/L) | 26.5 ± 14.9 | 24.8 ± 8.7 | 0.368 |
ALT(U/L) | 26.5 ± 18.0 | 26.3 ± 12.4 | 0.910 |
r-GT(U/L) | 39.0 ± 36.2 | 35.4 ± 32.9 | 0.515 |
hs-CRP (mg/L) | 1.7 ± 2.3 | 1.8 ± 2.8 | 0.667 |
Serum TNF-α (pg/mL) | 1.4 ± 1.4 | 1.6 ± 2.8 | 0.570 |