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Table 2 Pearson correlation of selected variables and basal cortisol level, post-dexamethasone cortisol level and number of glucocorticoid receptors in lymphocytes and monocytes in basal conditions and 16 weeks after a hypocaloric low glycemic index diet and metformin use in 16 subjects

From: Effects of caloric restriction and low glycemic index diets associated with metformin on glucose metabolism and cortisol response in overweight/obese subjects: a case series study

Variables Basal cortisol Post-dexamethasone cortisol Glucocorticoid receptorsb
Basal 16 weeks Basal 16 weeks Basal 16 weeks
r p r p r p r p r p r p
BMI a -0.44 0.09 0.50 0.05 0.28 0.80 0.35 0.22 0.88 0.02 -0.19 0.71
Glucose 0.39 0.14 -0.22 0.42 -0.33 0.38 -0.02 0.94 -0.59 0.22 -0.48 0.33
AUC glucosea -0.04 0.87 -0.19 0.49 -0.49 0.11 -0.49 0.07 -0.50 0.31 0.53 0.27
Insulin -0.21 0.43 -0.24 0.37 0.54 0.91 -0.11 0.71 0.76 0.08 -0.44 0.38
AUC insulina -0.20 0.45 -0.31 0.24 0.08 0.89 -0.21 0.46 0.94 0.005 -0.72 0.27
Cederholm index 0.06 0.83 0.11 0.68 0.15 0.74 0.38 0.18 -0.53 0.28 0.38 0.46
HOMA2-IRa -0.21 0.45 0.06 0.83 0.50 0.96 0.27 0.37 0.78 0.07 -0.58 0.23
HOMA2-%βa -0.38 0.16 0.17 0.54 0.56 0.57 0.09 0.76 0.75 0.09 -0.45 0.37
HOMA2-%Sa 0.01 0.97 -0.25 0.37 -0.40 0.50 -0.47 0.10 -0.75 0.07 0.75 0.09
Triglyceride -0.10 0.72 -0.37 0.16 -0.68 0.05 -0.56 0.04 0.05 0.92 0.16 0.76
VLDL-ca -0.09 0.73 -0.36 0.17 -0.67 0.05 -0.55 0.04 0.03 0.95 0.17 0.74
  1. aAbbreviations: BMI = body mass index; AUC glucose = area under the glycaemic curve; AUC insulin = area under the insulinaemic curve; HOMA2-%β = homeostasis model assessment β-cell function; HOMA2-IR = homeostasis model assessment insulin resistance; HOMA2-%S = homeostasis model assessment insulin sensitivity; VLDL-c = very low density lipoprotein cholesterol
  2. b6 subjects (4 male and 2 female)