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Table 2 Pearson correlation of selected variables and basal cortisol level, post-dexamethasone cortisol level and number of glucocorticoid receptors in lymphocytes and monocytes in basal conditions and 16 weeks after a hypocaloric low glycemic index diet and metformin use in 16 subjects

From: Effects of caloric restriction and low glycemic index diets associated with metformin on glucose metabolism and cortisol response in overweight/obese subjects: a case series study

Variables

Basal cortisol

Post-dexamethasone cortisol

Glucocorticoid receptorsb

Basal

16 weeks

Basal

16 weeks

Basal

16 weeks

r

p

r

p

r

p

r

p

r

p

r

p

BMI a

-0.44

0.09

0.50

0.05

0.28

0.80

0.35

0.22

0.88

0.02

-0.19

0.71

Glucose

0.39

0.14

-0.22

0.42

-0.33

0.38

-0.02

0.94

-0.59

0.22

-0.48

0.33

AUC glucosea

-0.04

0.87

-0.19

0.49

-0.49

0.11

-0.49

0.07

-0.50

0.31

0.53

0.27

Insulin

-0.21

0.43

-0.24

0.37

0.54

0.91

-0.11

0.71

0.76

0.08

-0.44

0.38

AUC insulina

-0.20

0.45

-0.31

0.24

0.08

0.89

-0.21

0.46

0.94

0.005

-0.72

0.27

Cederholm index

0.06

0.83

0.11

0.68

0.15

0.74

0.38

0.18

-0.53

0.28

0.38

0.46

HOMA2-IRa

-0.21

0.45

0.06

0.83

0.50

0.96

0.27

0.37

0.78

0.07

-0.58

0.23

HOMA2-%βa

-0.38

0.16

0.17

0.54

0.56

0.57

0.09

0.76

0.75

0.09

-0.45

0.37

HOMA2-%Sa

0.01

0.97

-0.25

0.37

-0.40

0.50

-0.47

0.10

-0.75

0.07

0.75

0.09

Triglyceride

-0.10

0.72

-0.37

0.16

-0.68

0.05

-0.56

0.04

0.05

0.92

0.16

0.76

VLDL-ca

-0.09

0.73

-0.36

0.17

-0.67

0.05

-0.55

0.04

0.03

0.95

0.17

0.74

  1. aAbbreviations: BMI = body mass index; AUC glucose = area under the glycaemic curve; AUC insulin = area under the insulinaemic curve; HOMA2-%β = homeostasis model assessment β-cell function; HOMA2-IR = homeostasis model assessment insulin resistance; HOMA2-%S = homeostasis model assessment insulin sensitivity; VLDL-c = very low density lipoprotein cholesterol
  2. b6 subjects (4 male and 2 female)