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Table 1 Cortisol levels in basal conditions and after suppression by dexamethasone; glucocorticoid receptors in lymphocytes and monocytes at baseline and 16 weeks after a hypocaloric low glycemic index diet and metformin use in 16 subjects

From: Effects of caloric restriction and low glycemic index diets associated with metformin on glucose metabolism and cortisol response in overweight/obese subjects: a case series study

Variables Baseline 16 weeks Δ p a
Mean SD Mean SD
Basal cortisol (μg/dL) 7.19 b 3.35 8.69 c 4.55 1.50 0.24
Post-dexamethasone cortisol (μg/dL) 4.27 b 2.85 5.99 c 5.31 1.72 0.02
Glucocorticoid receptors d 23,390 8052 26,650 9408 3260 0.66
  1. Data are expressed as mean and standard deviation (SD)
  2. a16 weeks vs. basal = paired Student t test
  3. bp < 0.001 basal cortisol vs. post-dexamethasone cortisol = paired Student t test
  4. c p = 0.01 basal cortisol vs. post-dexamethasone cortisol = Wilcoxon test
  5. d n = 6 subjects (4 male, 2 female)