Predictors of all-cause and cardiovascular disease mortality in type 2 diabetes: Diabetes Heart Study

Table 6 Addition of C-reactive protein and biventricular volume to model selected for cardiovascular disease mortality

Trait	Hazard Ratio	95 % Hazard Ratio Confidence Interval		p-value	Trait	Hazard Ratio	95 % Hazard Ratio Confidence Interval		p-value	Trait	Hazard Ratio	95 % Hazard Ratio Confidence Interval		p-value
Age	1.36	1.08	1.73	0.010	Age	1.63	1.27	2.10	1.20 × 10⁻⁴	Age	1.75	1.36	2.27	1.66 × 10⁻⁵
Female Sex	0.98	0.68	1.42	0.929	Female Sex	1.02	0.67	1.55	0.942	Female Sex	1.52	0.90	2.55	0.116
Coronary Artery Calcified Plaque	1.67	1.24	2.26	7.18 × 10⁻⁴	Coronary Artery Calcified Plaque	1.60	1.15	2.23	0.005	Coronary Artery Calcified Plaque	1.40	0.98	2.00	0.067
Urine Albumin: creatinine Ratio	1.52	1.32	1.75	7.59 × 10⁻⁹	Urine Albumin: creatinine Ratio	1.57	1.35	1.83	7.31 × 10⁻⁹	Urine Albumin: creatinine Ratio	1.45	1.24	1.70	3.29 × 10⁻⁶
History of Cardiovascular Disease	1.69	1.11	2.57	0.014	History of Cardiovascular Disease	1.52	0.95	2.43	0.084	History of Cardiovascular Disease	1.55	0.98	2.45	0.063
Diabetes Duration	1.20	0.98	1.46	0.082	Diabetes Duration	1.04	0.84	1.28	0.736	Diabetes Duration	1.09	0.88	1.36	0.435
					C-reactive Protein	1.19	0.93	1.51	0.167	Biventricular Volume	1.52	1.16	1.98	0.002

The cardiovascular disease mortality model was selected using a two-fold cross-validation approach in European Americans with type 2 diabetes. Hazards ratios (HRs) are for a one standard deviation change in the predictor (continuous variables) or change in group assignment (dichotomous variables). For medication use HRs, the HRs are for risk of mortality among those individuals using the given medication class

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