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Fig. 1 | Diabetology & Metabolic Syndrome

Fig. 1

From: High-fat diet feeding significantly attenuates anagliptin-induced regeneration of islets of Langerhans in streptozotocin-induced diabetic mice

Fig. 1

Effects of anagliptin on serum GLP-1, insulin, glucagon and beta-cell marker expressions in STZ-treated mice. a Serum GLP-1 levels in all mice were determined by ELISA. be The expressions of Pdx-1, MafA, NeuroD and Nkx6.1, beta cell marker genes, in each mouse pancreas were measured by real-time PCR. Data were calculated as values relative to the control (NF). f Serum insulin concentrations were measured by ELISA. g Serum glucagon concentrations were measured by ELISA. Quantitative data from 6 independent experiments are presented as bar graphs. *P < 0.05, Student’s t-test

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