Association of HSD11B1 polymorphic variants and adipose tissue gene expression with metabolic syndrome, obesity and type 2 diabetes mellitus: a systematic review

Table 5 Quality scores of studies included in the systematic review

Author, year	Case definition	Representativeness of the cases	Selection of controls	Definition of controls	Comparability	Ascertainment of exposure	Total
Alberti, 2007 [6]	+		+	+	+	++	++++++
Baudrand, 2010 [9]	+	+		+		++	+++++
Baudrand, 2011 [10]	+	+				+	+++
Desbriere, 2006 [15]	+			+		++	++++
Dujic, 2012	+	+	+	+		+++	+++++++
Engeli, 2004 [16]	+	+	+	+		+++	+++++++
Franks, 2004 [30]	+	+	+		+	+++	+++++++
Gandhi, 2013 [31]	+	+	+	+		++	++++++
Goedecke, 2006 [11]	+	+			+	+	++++
Gyllenhammer, 2014 [12]	+	+			++	+	+++++
Ku, 2009 [32]	+	+	+	+	+	+++	++++++++
Leyvraz, 2012 [17]	+	+				+	+++
Lindsay, 2003 [13]	+	+			+	++	+++++
Makkonen, 2007 [18]	+		+	+	+	++	++++++
Mariniello, 2006 [19]	+		+	+		++	+++++
Michailidou, 2007 [20]	+				+	++	++++
Michalaki, 2012 [7]	+			+		++	++++
Miyamoto, 2009 [2009]	+	+	+		+	++	++++++
Moon, 2011 [34]	+	+	+	+	+	+++	++++++++
Munoz, 2009 [8]	+	+				++	++++
Nair, 2004 [35]	+	+	+		+	+++	+++++++
Paulmyer-Lacroix, 2002 [21]	+	+	+	+		+++	+++++++
Paulsen, 2007 [22]	+			+		++	++++
Robitaille, 2004 [36]	+					+++	++++
Simonyte, 2009 [24]	+				+	++	++++
Simonyte, 2010 [23]	+	+			+	+	++++
Svendsen, 2009 [25]	+	+	+	+	++	++	++++++++
Tomlinson, 2002 [26]	+			+		++	++++
Tomlinson, 2008 [14]	+	+			++	+	+++++
Turek, 2014 [37]	+	+			+	++	+++++
Wake, 2003 [27]	+	+			++	+	+++++
Zha, 2009 [28]	+	+		+	+	++	++++++

ISSN: 1758-5996